Amyloid beta (Abeta) (AA 1-42) Peptide
Abeta
适用: 人
宿主: 合成
Quick Overview for Amyloid beta (Abeta) (AA 1-42) Peptide (ABIN2017638)
抗原
beta Amyloid (Abeta)
(Amyloid beta (Abeta))
宿主
人
资源
合成
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蛋白结构域
- AA 1-42
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序列
- DAEFRHDSGY EVHHQKLVFF AEDVGSNKGA IIGLMVGGVV IA
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特异性
- Formula: C203H311N55O60S1
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产品特性
- This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the 'longer forms' of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.
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纯度
- > 95 %
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限制
- 仅限研究用
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溶解方式
- Insoluble in water, may be dissolved in any buffer of pH >9.
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储存条件
- -20 °C
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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分子量
- 4514.100 kDa
抗原
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