Charged Multivesicular Body Protein 5 (CHMP5) (C-Term) Peptide
CHMP5
适用: 人, 小鼠
宿主: 合成
BP, WB
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- 抗原 See all CHMP5 products
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
- 蛋白结构域
- C-Term
- 宿主
- 人, 小鼠
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- Synthetic peptide located within the following region: < a href='http://www.ncbi.nlm.nih.gov/blast/Blast.cgi?PROGRAM=blastp&CLIENT=web&SERVICE=plain&PAGE=Proteins&CMD=Put&DATABASE=nr&CDD_SEARCH=1&AUTO_FORMAT=Semi-auto&SHOW_OVERVIEW=on&SHOW_LINKOUT=on&GET_SEQUENCE=on&NCBI_GI=on&ALIGNMENTS =50&I_THRESH=0.005&QUERY=
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-Chmp5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Charged Multivesicular Body Protein 5 (CHMP5) peptide
CHMP5 适用: 人, 小鼠, Cow, 大鼠 宿主: 合成 BP, Imm
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
- 别名
- SNF7DC2 Peptide, cgi-34 Peptide, hspc177 Peptide, pnas-2 Peptide, vps60 Peptide, chmp5 Peptide, zgc:64125 Peptide, C9orf83 Peptide, HSPC177 Peptide, PNAS-2 Peptide, Vps60 Peptide, 2210412K09Rik Peptide, AW545668 Peptide, RGD1305968 Peptide, charged multivesicular body protein 5 S homeolog Peptide, charged multivesicular body protein 5b Peptide, charged multivesicular body protein 5 Peptide, charged multivesicular body protein 5 L homeolog Peptide, chromatin modifying protein 5 Peptide, chmp5.S Peptide, chmp5b Peptide, CHMP5 Peptide, chmp5.L Peptide, chmp5 Peptide, Chmp5 Peptide
- 背景
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Chmp5 is a probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
Alias Symbols: 2210412K09Rik, AW545668
Protein Size: 219 - 分子量
- 24 kDa
- 基因ID
- 76959
- NCBI登录号
- NM_029814, NP_084090
- UniProt
- Q9D7S9
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