Mucin 1 (MUC1) (C-Term) Peptide
MUC1
适用: 人
宿主: 合成
BP, IHC
Quick Overview for Mucin 1 (MUC1) (C-Term) Peptide (ABIN1540997)
抗原
MUC1
(Mucin 1 (MUC1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Immunohistochemistry (IHC)
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蛋白结构域
- C-Term
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序列
- GCAGHCLSHC LGCLSVPPKE LRAAGHLSSP GYLPSYERVP HLPHPWALCA
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MUC1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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Mucin 1 (MUC1) peptide (Ovalbumin)
MUC1 适用: 人 宿主: 合成 WB, Imm, SDS
Mucin 1 (MUC1) (AA 902-941) peptide (His tag)MUC1 适用: 人 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MUC1 (Mucin 1 (MUC1))
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背景
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This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
Alias Symbols: CD227, EMA, H23AG, KL-6, MAM6, PEM, PEMT, PUM, MUC-1, MUC-1/X, MUC1/ZD, MUC-1/SEC
Protein Size: 158 -
分子量
- 14 kDa
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基因ID
- 4582
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NCBI登录号
- NM_001044393, NP_001037858
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UniProt
- Q7Z538
抗原
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