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CAMP Responsive Element Modulator (CREM) (C-Term) Peptide

CREM 适用: 人, 大鼠 宿主: 合成 BP, WB
产品编号 ABIN1540899
发货至: 中国
  • 抗原 See all CREM products
    CREM (CAMP Responsive Element Modulator (CREM))
    蛋白结构域
    C-Term
    宿主
    人, 大鼠
    资源
    • 6
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE
    产品特性
    This is a synthetic peptide designed for use in combination with anti-Crem Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CREM (CAMP Responsive Element Modulator (CREM))
    别名
    CREM Peptide, ICER Peptide, CREM-2 Peptide, hCREM-2 Peptide, ICERI Peptide, Icer Peptide, cAMP responsive element modulator Peptide, CREM Peptide, Crem Peptide
    背景
    Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.

    Alias Symbols: Icer

    Protein Size: 357
    分子量
    39 kDa
    基因ID
    25620
    NCBI登录号
    NM_001110860, NP_001104330
    UniProt
    Q03061
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