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CAMP Responsive Element Modulator (CREM) (C-Term) Peptide

CREM 适用: 人, 大鼠 宿主: 合成 BP, WB
产品编号 ABIN1540899
发货至: 中国
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Quick Overview for CAMP Responsive Element Modulator (CREM) (C-Term) Peptide (ABIN1540899)

抗原

CREM (CAMP Responsive Element Modulator (CREM))

宿主

人, 大鼠

资源

  • 6
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    C-Term

    序列

    KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE

    产品特性

    This is a synthetic peptide designed for use in combination with anti-Crem Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    CREM (CAMP Responsive Element Modulator (CREM))

    背景

    Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.

    Alias Symbols: Icer

    Protein Size: 357

    分子量

    39 kDa

    基因ID

    25620

    NCBI登录号

    NM_001110860, NP_001104330

    UniProt

    Q03061
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