CAMP Responsive Element Modulator (CREM) (C-Term) Peptide
CREM
适用: 人, 大鼠
宿主: 合成
BP, WB
Quick Overview for CAMP Responsive Element Modulator (CREM) (C-Term) Peptide (ABIN1540899)
抗原
CREM
(CAMP Responsive Element Modulator (CREM))
宿主
人, 大鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Crem Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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CAMP Responsive Element Modulator (CREM) peptide
CREM 适用: 人, 大鼠, Cow, 小鼠 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CREM (CAMP Responsive Element Modulator (CREM))
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背景
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Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.
Alias Symbols: Icer
Protein Size: 357 -
分子量
- 39 kDa
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基因ID
- 25620
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NCBI登录号
- NM_001110860, NP_001104330
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UniProt
- Q03061
抗原
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