PDZD3 产品
(PDZ Domain Containing 3 (PDZD3))
Categories
Guanylyl cyclase C (GCC, or GUCY2C\; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR\; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).[supplied by OMIM, Mar 2008].
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Featured PDZD3 Categories
Recommended PDZD3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN529096
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7160813
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (2)
Cat. No.
ABIN949657
Quantity
100 μL
Datasheet
Datasheet
Recommended PDZD3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1314608
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3084313
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3128056
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our PDZD3 Products
: "Olfactory deficits in Niemann-Pick type C1 (NPC1) disease." in: PLoS ONE, Vol. 8, Issue 12, pp. e82216, (2014) (PubMed).Synonyms and alternative names related to PDZD3
PDZ domain containing 3 (Pdzd3), PDZ domain containing 3b (pdzd3b), PDZ domain containing 3 (PDZD3), IKEPP, NaPi-Cap2, NHERF4, PDZK2, Pdzk2, RGD1559807, zgc:194812Protein level used designations for PDZD3
- Na(+)/H(+) exchange regulatory cofactor NHE-RF4
- PDZ domain containing 3
- NHERF-4
- PDZ domain containing 2
- PDZ domain-containing protein 2
- PDZ domain-containing protein 3
- intestinal and kidney enriched PDZ protein
- intestinal and kidney-enriched PDZ protein
- na/Pi cotransporter C-terminal-associated protein 2
- naPi-Cap2
- natrium-phosphate cotransporter IIa C-terminal-associated protein 2
- sodium-hydrogen exchanger regulatory factor 4
- sodium-phosphate cotransporter IIa C-terminal-associated protein 2
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