电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PCDHG 抗体 (C-Term, Cytoplasmic Domain, pan)

This anti-PCDHG antibody (ABIN5539938) is a Mouse Monoclonal antibody detecting PCDHG in ICC, IF, WB. Suitable for Mouse, Rat.
产品编号 ABIN5539938
发货至: 中国

Quick Overview for PCDHG 抗体 (C-Term, Cytoplasmic Domain, pan) (ABIN5539938)

抗原

PCDHG (Protocadherin gamma Cluster (PCDHG))

适用

小鼠, 大鼠

宿主

小鼠

克隆类型

单克隆

应用范围

Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)

克隆位点

S159-5
  • 抗原表位

    AA 808-931, C-Term, Cytoplasmic Domain, pan

    特异性

    This antibody detects a ~100 kDa protein. Cross-reacts with all Gamma- protocadherin-A, -B and -C proteins. Species: Mouse and Rat.

    纯化方法

    Protein G Chromatography

    免疫原

    Fusion protein corresponding to amino acids 808-931 (C-terminal cytoplasmic constant domain) of mouse Protocadherin-gamma-A1 that is shared by all 22 Gamma-protocadherins (A-subfamily: amino acids ~807-930, B-subfamily: amino acids ~789-912 and C subfamily).

    亚型

    IgG1
  • 应用备注

    Western blot: 1/1000, 1 μg/mL was sufficient for detection of PCDHG (pan) in 20 μg of Rat brain lysate by colorimetric immunoblot analysis using HRP conjugated secondary antibody. Immunocytochemistry .

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.4, 50 % Glycerol, 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
  • 抗原

    PCDHG (Protocadherin gamma Cluster (PCDHG))

    别名

    pcdhg

    背景

    The protocadherin gamma gene cluster is one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

    基因ID

    93709

    UniProt

    Q91XZ0
You are here:
Chat with us!