PBX1 抗体
(Pre-B-Cell Leukemia Homeobox Protein 1 (PBX1))
This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1\;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
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Latest Publications for our PBX1 抗体
: "The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1." in: Cell reports, Vol. 14, Issue 5, pp. 1156-1168, (2016) (PubMed).: "Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion." in: Nature communications, Vol. 6, pp. 10044, (2015) (PubMed).
: "Copy number aberrations of genes regulating normal thymus development in thymic epithelial tumors." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 8, pp. 1960-71, (2013) (PubMed).
: "Cooperative transcriptional activation by Klf4, Meis2, and Pbx1." in: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3723-33, (2011) (PubMed).
: "PBX1 genomic pioneer function drives ER? signaling underlying progression in breast cancer." in: PLoS genetics, Vol. 7, Issue 11, pp. e1002368, (2011) (PubMed).
: "Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation." in: Human molecular genetics, Vol. 18, Issue 4, pp. 679-87, (2009) (PubMed).
: "Gfi1 integrates progenitor versus granulocytic transcriptional programming." in: Blood, Vol. 113, Issue 22, pp. 5466-75, (2009) (PubMed).
: "Evaluating the association of common PBX1 variants with type 2 diabetes." in: BMC medical genetics, Vol. 9, pp. 14, (2008) (PubMed).
: "Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer." in: Cancer research, Vol. 68, Issue 21, pp. 8852-60, (2008) (PubMed).
: "Pre-B-cell leukemia transcription factor 1 regulates expression of valosin-containing protein, a gene involved in cancer growth." in: The American journal of pathology, Vol. 170, Issue 1, pp. 152-9, (2007) (PubMed).
Aliases for PBX1 抗体
PBX homeobox 1 (PBX1) 抗体pre-B-cell leukemia homeobox 1a (pbx1a) 抗体
pre B cell leukemia homeobox 1 (Pbx1) 抗体
PBX homeobox 1 (Pbx1) 抗体
pre-B-cell leukemia homeobox 1 S homeolog (pbx1.S) 抗体
2310056B04Rik 抗体
AI848790 抗体
AU015730 抗体
D230003C07Rik 抗体
fi29e01 抗体
Pbx-1 抗体
Pbx1a 抗体
PBX1A 抗体
pbx1b 抗体
Pbx1b 抗体
wu:fi29e01 抗体
Xpbx1 抗体
Xpbx1b 抗体
zgc:55265 抗体
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