PDL1 ELISA Matched Antibody Pair (Risk Free)
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- 抗原 See all PD-L1 products
- PD-L1 (CD274 (PD-L1))
- 片段
- single-domain Antibody (sdAb)
- 抗原表位
- Extracellular Domain
- 适用
- 人
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宿主
- Various Hosts
- 克隆类型
- 单克隆
- 应用范围
- ELISA
- 品牌
- Risk-Free™
- 产品特性
- Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.
- 纯化方法
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Mouse Monoclonal: Antibodies supplied as protein A purified IgG1.
Single Domain: Antibodies supplied as affinity chromatography purified via nickel column. - 组件
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Capture: PD-L1 Antibody [4F2]
Detection: PD-L1 Antibody [F6A9] - 免疫原
- PD-L1 antibodies were raised against the extracellular domain of human PD-L1.
- 克隆位点
- 4F2-F6A9
- 亚型
- IgG1
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CD274 (Human) Matched Antibody Pair
ELISA 适用: 人 ELISA unconjugated 宿主: 小鼠
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- 说明
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Risk-Free™ antibodies are monoclonal antibodies made to improve in vitro studies.
Unlike antibodies developed using proteins made in yeast or bacteria, Risk-Free™ antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein.
These antibodies have the following advantages:
- Antibodies are developed against mammalian-expressed, post-translationally modified recombinant proteins.
- Multiple antibodies per target allows the user to choose the best antibody for their application
- Available individually or as a set
- Risk-Free™ means they are rigorously tested and guaranteed to work for their designated applications:
- ELISA
- Flow Cytometry
- Immunoblot
- Immunohistochemistry
- Immunocytochemistry
- Immunofluorescence - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存方法
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Mouse Monoclonal: Antibodies can be stored at 4 ˚C for three months and -20 ˚C, stable for up to one year.
Single Domain: Antibody should be stored in working aliquots at -20°C, stable for up to one year.
As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- PD-L1 (CD274 (PD-L1))
- 别名
- PDL1 (PD-L1 产品)
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