anti-Interleukin 1 alpha (IL1A) antibody pair
Our Local Distributor
北京 101111
Quick Overview for anti-Interleukin 1 alpha (IL1A) antibody pair (ABIN1305225)
抗原
适用
宿主
克隆类型
应用范围
-
-
实验类型
- Sandwich ELISA
-
检测范围
- 15.6-2000 pg/mL
-
最低检测浓度
- 15.6 pg/mL
-
特异性
- Detects mouse IL-1alpha.
-
无交叉反应
- 人
-
交叉反应 （详细）
- Does not detect human IL-1alpha or mouse IL-1beta.
-
灵敏度
- 10 pg/mL
-
组件
- 1 vial standard protein (1μg) (lyophilized) [STD] 1 vial coating antibody (120μg) [COAT] 1 vial detection antibody (30μg) [DET] 1 vial streptavidin-HRP (10μg) (lyophilized) [STREP]
-
-
IL1A (Human) Matched Antibody Pair
ELISA 适用: 人 ELISA unconjugated 宿主: 兔, 小鼠
IL1A (Human) IP-WB Antibody PairIP 适用: 人 IP unconjugated 宿主: 兔, 小鼠
IL1A (Human) Matched Antibody PairELISA 适用: 人 ELISA unconjugated 宿主: 兔, 小鼠
IL1A (Human) Matched Antibody PairELISA 适用: 人 ELISA unconjugated 宿主: 小鼠
-
-
限制
- 仅限研究用
-
-
-
浓度
- Lot specific
-
储存条件
- -20 °C
-
储存方法
-
Short Term Storage: -20°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
-
-
- IL1A (Interleukin 1 alpha (IL1A))
-
别名
- IL-1alpha
-
背景
- The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions, but also acts locally in a membrane-bound form by activating IL-1R1. Additionally, passive release of IL-1alpha upon cell death can trigger a sterile inflammatory response to dying cells. The cleavage of IL-1alpha is not mediated by caspase-1 and is not required for binding to IL-1R1. Recently it has been observed that all activators of the inflammasome NLRP3/NALP3 induce the simultaneous secretion of IL-1alpha and IL-1beta. Although most activators fully rely on the inflammasome for IL-1alpha secretion, some induce the processing and secretion of IL-1alpha in an inflammasome-independent manner.
-
UniProt
- P01582
抗原
-
