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抗Human C-MYC 抗体:
抗Rat (Rattus) C-MYC 抗体:
抗Mouse (Murine) C-MYC 抗体:
Human Monoclonal C-MYC Primary Antibody for FM, IHC (fro) - ABIN967320
Blackwood, Eisenman: Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. in Science (New York, N.Y.) 1991
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Chicken Monoclonal C-MYC Primary Antibody for ChIP, CyTOF - ABIN152253
Locker, Dowle, Ellis, Elston, Blamey, Sikora, Evan, Robins: c-myc oncogene product expression and prognosis in operable breast cancer. in British journal of cancer 1989
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Human Monoclonal C-MYC Primary Antibody for FACS, IHC (p) - ABIN302092
Veracini, Simon, Richard, Schraven, Horejsi, Roche, Benistant: The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1. in The Journal of cell biology 2008
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Human Monoclonal C-MYC Primary Antibody for FACS, IHC (p) - ABIN302017
Wang, Campoli, Ko, Luo, Ferrone: Enhancement of scFv fragment reactivity with target antigens in binding assays following mixing with anti-tag monoclonal antibodies. in Journal of immunological methods 2004
Show all 15 Pubmed References
All Species Monoclonal C-MYC Primary Antibody for FACS, IP - ABIN2749043
Persson, Hennighausen, Taub, DeGrado, Leder: Antibodies to human c-myc oncogene product: evidence of an evolutionarily conserved protein induced during cell proliferation. in Science (New York, N.Y.) 1984
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All Species Monoclonal C-MYC Primary Antibody for IHC, IHC (p) - ABIN4994828
Hilpert, Hansen, Wessner, Küttner, Welfle, Seifert, Höhne: Anti-c-myc antibody 9E10: epitope key positions and variability characterized using peptide spot synthesis on cellulose. in Protein engineering 2001
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Human Monoclonal C-MYC Primary Antibody for IHC (fro), IF - ABIN2477762
Quant, Woo: Normal values of eye position in the Chinese population of Hong Kong. in Optometry and vision science : official publication of the American Academy of Optometry 1992
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Human Monoclonal C-MYC Primary Antibody for FACS, IHC (p) - ABIN536092
Fujiwara, Poikonen, Aleman, Valtavaara, Saksela, Mayer: A single-chain antibody/epitope system for functional analysis of protein-protein interactions. in Biochemistry 2002
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Human Polyclonal C-MYC Primary Antibody for IF (cc), IF (p) - ABIN1387773
Gao, Zhao, Song, Yang: Expression pattern of embryonic stem cell markers in DFAT cells and ADSCs. in Molecular biology reports 2012
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mdig (显示 MINA 抗体) directly interacts with c-myc and JAK1 (显示 JAK1 抗体) in multiple myeloma (MM) cell lines, which contributes to hyperactivation of the IL-6 (显示 IL6 抗体)-JAK (显示 JAK3 抗体)-STAT3 (显示 STAT3 抗体) signaling important for the pathogenesis of MM.
we suggested that P2X7R (显示 P2RX7 抗体) and NLRP3 (显示 NLRP3 抗体) inflammasome are over-expressed in HNSCC and that the degree of expressional level may represent prognosis of patients.
we show that transcription of the LMP1 (显示 PDLIM7 抗体) gene can be negatively regulated by a host transcription factor, c-Myc.
While TP53 (显示 TP53 抗体) mutation and MYC amplification were synergistic in promoting tumor progression, PIK3CA (显示 PIK3CA 抗体) mutation was found to have alleviated the oncogenic effect of either the TP53 (显示 TP53 抗体) mutation or MYC amplification, and was associated with a significant reduction in mitotic activity in TP53 (显示 TP53 抗体) mutated and/or MYC amplified breast cancer
Mechanistic investigations demonstrated that SNHG3 functioned as a competing endogenous RNA (ceRNA) to 'sponge' miR (显示 MLXIP 抗体)-182-5p, thus leading to the release of c-Myc from miR (显示 MLXIP 抗体)-182-5p and modulating the expression of c-Myc. In conclusion, SNHG3 promoted CRC (显示 CALR 抗体) progression via sponging miR (显示 MLXIP 抗体)-182-5p and upregulating c-Myc and its target genes
Study identifies Eya3 (显示 EYA3 抗体) as a regulator of PP2A (显示 PPP2R4 抗体), a major cellular Ser (显示 SIGLEC1 抗体)/Thr (显示 TRH 抗体) phosphatase, and uncovers a mechanism of controlling the stability of a critical oncogene (显示 RAB1A 抗体), c-Myc.
By establishing c-Myc as a direct target of miR (显示 MLXIP 抗体)-449a, the authors revealed that miR (显示 MLXIP 抗体)-449a enhanced radiosensitivity by repressing c-Myc expression in LNCaP prostate cancer cells.
Baseline enhancer activity of the conserved region specifically on the MYC promoter and its further positive modulation by the SNP risk-allele was shown in vitro. Our findings implicate MYC deregulation as the underlying cause of the observed association.
Here the authors show that sublethal activation of Caspase-3 (显示 CASP3 抗体) plays an essential, facilitative role in Myc-induced genomic instability and oncogenic transformation.
Our findings indicate that Prdx2 (显示 PRDX2 抗体) might have an important role in the regulation of trophoblast proliferation and apoptosis during early pregnancy, and that its expression is mediated by c-Myc. Thus, these two proteins may be involved in the pathogenesis of RM and may represent potential therapeutic targets
Ouabain-induced proliferation might be attributed, at least in part, to decrease of intracellular free calcium and increase of c-myc mRNA expression, and that may be directly or indirectly involved in regulation of blood pressure.
report the isolation of complete coding regions of rabbit SOX2, KLF4, C-MYC and NANOG, which encode transcription factors that play crucial regulatory roles during early mammalian embryonic development
Using inducible genetic mosaics, we overexpressed Myc in the epicardium and determined the differential expansion of Myc-overexpressing cells with respect to their wild type counterparts. Myc-overexpressing cells overcolonized all epicardial-derived lineages and showed increased ability to invade the myocardium and populate the vasculature.
Nac1 (显示 NACC1 抗体) overexpression promotes ESC proliferation and delays ESC differentiation in the absence of leukemia inhibitory factor (LIF (显示 LIF 抗体)). Furthermore, we demonstrated that Nac1 (显示 NACC1 抗体) directly binds to the c-Myc promoter and regulates c-Myc transcription.
this study demonstrates that miR (显示 MLXIP 抗体)-451 regulates T cell proliferative responses in part via a Myc-dependent mechanism
AKAP1 (显示 AKAP1 抗体) is a transcriptional target of Myc, and it supports mTOR (显示 FRAP1 抗体) pathway and the growth of cancer cells.
Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4 (显示 POU5F1 抗体), c-Myc, Sox2 (显示 SOX2 抗体) and Klf4 (显示 KLF4 抗体).
High c-myc expression is associated with gliomagenesis.
In a mouse lung model of KRas(G12D)-driven adenomas, co-activation of Myc drives the immediate transition to highly proliferative and invasive adenocarcinomas marked by highly inflammatory, angiogenic, and immune-suppressed stroma.
the role of phosphorylation on AID serine38 in AID activity at the Immunoglobulin switch region and off-target Myc gene, is reported.
This study demonstrates that LMP2A uses the role of MYC in the cell cycle, particularly in the p27(kip1 (显示 CDKN1B 抗体)) degradation process, to accelerate lymphomagenesis in vivo.
Results show Myc to be dispensable for sustained in vivo hepatocyte proliferation but necessary for maintaining normal lipid homeostasis.
Apoptosis was also observed with myca expression; introduction of homozygous tp53 (显示 TP53 抗体)(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.
MYC down-regulation induces mitochondrial apoptosis in T lymphoblasts.
These findings not only reveal a novel role of Mad1 (显示 MXD1 抗体) in regulating developmental cell death but also suggest that a balance of Mad and Myc controls cell fate determination during adult organ development.
Thyroid hormone (显示 PTH 抗体) activates protein arginine methyltransferase 1 expression by directly inducing c-Myc transcription during Xenopus intestinal stem cell development.(
c-Myc has a direct role in the control of DNA replication
Findings support a model in which Myc, Twist and Slug/Snail2 function in a regulatory circuit within lateral plate mesoderm that directs normal vessel formation in both the vascular and lymphatic systems.
Expression of Drosophila Myc (dMyc) suppresses, whereas loss of dMyc enhances, ectopically activated JNK (显示 MAPK8 抗体) signaling-induced cell death. dMyc impedes physiologically activated JNK (显示 MAPK8 抗体) pathway-mediated cell death. Loss of dMyc triggers JNK (显示 MAPK8 抗体) pathway activation and JNK (显示 MAPK8 抗体)-dependent cell death.
tissue-specific downregulation of the Drosophila homolog of human c-myc proto-oncogene (dMyc) suppresses tau-mediated morphological and functional deficits by reducing abnormal tau hyperphosphorylation and restoring the heterochromatin loss.
dMyc has an essential role in preventing JNK (显示 MAPK8 抗体)-mediated retinal glial activation
the key target of the Psi/MED network in controlling developmentally regulated tissue growth is the transcription factor MYC.
Myc dosage plays crucial role in determining sex-specific size in Drosophila larvae and adult tissue. Double dose of Myc in females serves at least twice in development to promote sexual size dimorphism.
BicC (显示 BICC1 抗体) down regulates Myc in the Malpighian tubule.
activation of the TOR-Myc axis in midgut stem and progenitor cells influences a variety of traits in Drosophila
Drosophila adult muscle precursors display homing behavior to muscle niche and the niche-driven Insulin (显示 INS 抗体)-Notch (显示 NOTCH1 抗体)-dMyc cascade plays a key role in setting the activated state of adult muscle precursors.
a functional link between Myc, a renowned oncogene (显示 RAB1A 抗体), and the essential nucleotide biosynthetic enzyme CTPsyn.
MYC and S6K (显示 RPS6KB1 抗体) cooperate through coordinate activation of the essential Pol I transcription initiation factor TIF-1A (显示 RRN3 抗体).
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
avian myelocytomatosis viral oncogene homolog
, class E basic helix-loop-helix protein 39
, myc proto-oncogene protein
, myc-related translation/localization regulatory factor
, proto-oncogene c-Myc
, transcription factor p64
, v-myc myelocytomatosis viral oncogene homolog
, c-myc proto-oncogene
, avian myelocytomatosis viral (v-myc) oncogene homolog
, Avian myelocytomatosis viral (v-myc) oncogene homolog
, myelocytomatosis viral oncogene homolog
, v-myc avian myelocytomatosis viral oncogene homolog
, cellular myelocytomatosis oncogene
, Proto-oncogene c-Myc
, Transcription factor p64
, transcriptional regulator Myc-A
, MYC II
, transcriptional regulator Myc-B
, Myc proto-oncogene protein
, CG10798 gene product from transcript CG10798-RB
, Diminutive protein
, lethal (1) G0354
, lethal (1) G0359