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抗Human C-MYC 抗体:
抗Rat (Rattus) C-MYC 抗体:
抗Mouse (Murine) C-MYC 抗体:
Chicken Monoclonal C-MYC Primary Antibody for ChIP, CyTOF - ABIN152253
Locker, Dowle, Ellis, Elston, Blamey, Sikora, Evan, Robins: c-myc oncogene product expression and prognosis in operable breast cancer. in British journal of cancer 1989
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Human Monoclonal C-MYC Primary Antibody for FACS, IHC (p) - ABIN302017
Veracini, Simon, Richard, Schraven, Horejsi, Roche, Benistant: The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1. in The Journal of cell biology 2008
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Human Monoclonal C-MYC Primary Antibody for FACS, IHC (p) - ABIN302092
Wang, Campoli, Ko, Luo, Ferrone: Enhancement of scFv fragment reactivity with target antigens in binding assays following mixing with anti-tag monoclonal antibodies. in Journal of immunological methods 2004
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All Species Monoclonal C-MYC Primary Antibody for FACS, IP - ABIN2749043
Persson, Hennighausen, Taub, DeGrado, Leder: Antibodies to human c-myc oncogene product: evidence of an evolutionarily conserved protein induced during cell proliferation. in Science (New York, N.Y.) 1984
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Human Polyclonal C-MYC Primary Antibody for ELISA, ICC - ABIN6263457
Tang, Peng, Huang, Xie, Chen, Shen, Gao, You, Xie, Chen: Neoisoliquiritigenin Inhibits Tumor Progression by Targeting GRP78-β- catenin Signaling in Breast Cancer. in Current cancer drug targets 2018
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Human Monoclonal C-MYC Primary Antibody for IF, IHC (p) - ABIN533219
Huang, Bredemeyer, Walker, Bassing, Sleckman: Dynamic regulation of c-Myc proto-oncogene expression during lymphocyte development revealed by a GFP-c-Myc knock-in mouse. in European journal of immunology 2008
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Human Monoclonal C-MYC Primary Antibody for FACS, IHC (p) - ABIN536092
Fujiwara, Poikonen, Aleman, Valtavaara, Saksela, Mayer: A single-chain antibody/epitope system for functional analysis of protein-protein interactions. in Biochemistry 2002
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Human Monoclonal C-MYC Primary Antibody for IHC (fro), IF - ABIN2477762
Quant, Woo: Normal values of eye position in the Chinese population of Hong Kong. in Optometry and vision science : official publication of the American Academy of Optometry 1992
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Human Monoclonal C-MYC Primary Antibody for IF, WB - ABIN3201011
Khanna, Böckelman, Hemmes, Junttila, Wiksten, Lundin, Junnila, Murphy, Evan, Haglund, Westermarck, Ristimäki: MYC-dependent regulation and prognostic role of CIP2A in gastric cancer. in Journal of the National Cancer Institute 2009
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MACC1 (显示 MACC1 抗体) and c-Myc are highly expressed in serum and tumor tissues of EC patients. Both are correlated with TNM (显示 ODZ1 抗体) stage, primary infiltration, and lymph node or distal metastasis.
study provides an interesting example using chemical biological approaches for determining distinct biological consequences from inhibiting vs. activating an E3 ubiquitin ligase (显示 MUL1 抗体) and suggests a potential broad therapeutic strategy for targeting c-MYC in cancer treatment by pharmacologically modulating cIAP1 (显示 BIRC2 抗体) E3 ligase activity.
The data demonstrated that 10058F4, a cMyc inhibitor, increased the growth inhibition, G0/G1 phase arrest and apoptosis of the NALM6 and CEM cells as induced by dexamethasone (DXM), a type of GC.
c-MYC/BCL2 (显示 BCL2 抗体) protein co-expression is associated with non-germinal center B-cell in Diffuse Large B-Cell Lymphoma
c-Myc was capable of upregulating HP1gamma (显示 CBX3 抗体) by directly binding to the E-box element in the first intron of HP1gamma (显示 CBX3 抗体) gene, and the upregulated HP1gamma (显示 CBX3 抗体), in turn, repressed the expression of miR (显示 MLXIP 抗体)-451a by enhancing H3K9 methylation at the promoter region of miR (显示 MLXIP 抗体)-451a.
A subset of pancreatic acinar cell carcinomas shows c-MYC alterations including gene amplification and chromosome 8 polysomy.
Expression and Clinical Significance of LC-3 and P62 in Non-small Cell Lung Cancer
The findings of the current study demonstrate presence of the IDH1 (显示 IDH1 抗体) R132H mutation in primary human glioblastoma cell lines with upregulated HIF-1alpha (显示 HIF1A 抗体) expression, downregulating c-MYC activity and resulting in a consequential decrease in miR (显示 MLXIP 抗体)-20a, which is responsible for cell proliferation and resistance to standard temozolomide treatment.
a novel signal circuit of Stat3 (显示 STAT3 抗体)/Oct-4 (显示 POU5F1 抗体)/c-Myc was identified for regulating stemness-mediated Doxorubicin resistance in triple-negative breast cancer
MYC amplification and MYC overexpression occurred almost exclusively in secondary cutaneous angiosarcoma in our series.
Ouabain-induced proliferation might be attributed, at least in part, to decrease of intracellular free calcium and increase of c-myc mRNA expression, and that may be directly or indirectly involved in regulation of blood pressure.
report the isolation of complete coding regions of rabbit SOX2, KLF4, C-MYC and NANOG, which encode transcription factors that play crucial regulatory roles during early mammalian embryonic development
The data supports an indispensable role for Mule in cardiac homeostasis through the regulation of mitochondrial function via maintenance of Pgc-1alpha and Pink1 (显示 PINK1 抗体) expression and persistent negative regulation of c-Myc.
MYC binding is enriched at neuroendocrine genes in tumor cells and loss of MYC reduces ductal-neuroendocrine lineage heterogeneity, while deregulated MYC expression in KRAS mutants increases this phenotype.
Although either BCR (显示 BCR 抗体) or CD40 (显示 CD40 抗体) ligation induced c-Myc in naive B cells, both signals were required to highly induce c-Myc, a critical mediator of GC B (显示 NPR2 抗体) cell survival and cell cycle reentry.
Myc is a component that links neuromesodermal progenitors maintenance and pre-somitic mesoderm maturation during the body axis elongation stages of mouse embryogenesis.
Myc potentiates the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signalling pathway, which cooperates with the transcriptional regulatory network in sustaining embryonic stem cell self-renewal.
Although mnt heterozygosity clearly slowed lymphomagenesis in vavP-MYC10 and Emu-myc mice, the change(s) in cellular properties responsible for this effect remain to be identified.
clusters of enhancers, such as BENC in the myc gene, form highly combinatorial systems that allow precise control of gene expression across normal cellular hierarchies and which also can be hijacked in malignancies
Conditional deletion of Myc in hyaloid vascular endothelial cells suppressed both proliferation and cell death.
c-Myc repression during development is crucial for the maturation of preacinar cells, and c-Myc overexpression can contribute to pancreatic carcinogenesis through the induction of a dedifferentiated state.
MYC negatively regulated the expression of genes involved in mitochondrial biogenesis and maintenance but positively regulated genes involved in DNA and histone methylation. Knockdown of MYC in colorectal cancer cells reset the altered metabolism and suppressed cell growth.
Methylparabens exposure increased malformations, LPO, apoptosis, ccnd1 and myca expressions, and decreased GST activities and NO levels compared with the control group.
Apoptosis was also observed with myca expression; introduction of homozygous tp53 (显示 TP53 抗体)(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.
MYC down-regulation induces mitochondrial apoptosis in T lymphoblasts.
These findings not only reveal a novel role of Mad1 (显示 MXD1 抗体) in regulating developmental cell death but also suggest that a balance of Mad and Myc controls cell fate determination during adult organ development.
Thyroid hormone (显示 PTH 抗体) activates protein arginine methyltransferase 1 expression by directly inducing c-Myc transcription during Xenopus intestinal stem cell development.(
c-Myc has a direct role in the control of DNA replication
Findings support a model in which Myc, Twist and Slug/Snail2 function in a regulatory circuit within lateral plate mesoderm that directs normal vessel formation in both the vascular and lymphatic systems.
Expression of Drosophila Myc (dMyc) suppresses, whereas loss of dMyc enhances, ectopically activated JNK (显示 MAPK8 抗体) signaling-induced cell death. dMyc impedes physiologically activated JNK (显示 MAPK8 抗体) pathway-mediated cell death. Loss of dMyc triggers JNK (显示 MAPK8 抗体) pathway activation and JNK (显示 MAPK8 抗体)-dependent cell death.
tissue-specific downregulation of the Drosophila homolog of human c-myc proto-oncogene (dMyc) suppresses tau-mediated morphological and functional deficits by reducing abnormal tau hyperphosphorylation and restoring the heterochromatin loss.
dMyc has an essential role in preventing JNK (显示 MAPK8 抗体)-mediated retinal glial activation
the key target of the Psi/MED network in controlling developmentally regulated tissue growth is the transcription factor MYC.
Myc dosage plays crucial role in determining sex-specific size in Drosophila larvae and adult tissue. Double dose of Myc in females serves at least twice in development to promote sexual size dimorphism.
BicC (显示 BICC1 抗体) down regulates Myc in the Malpighian tubule.
activation of the TOR-Myc axis in midgut stem and progenitor cells influences a variety of traits in Drosophila
Drosophila adult muscle precursors display homing behavior to muscle niche and the niche-driven Insulin (显示 INS 抗体)-Notch (显示 NOTCH1 抗体)-dMyc cascade plays a key role in setting the activated state of adult muscle precursors.
a functional link between Myc, a renowned oncogene (显示 RAB1A 抗体), and the essential nucleotide biosynthetic enzyme CTPsyn.
MYC and S6K (显示 RPS6KB1 抗体) cooperate through coordinate activation of the essential Pol I transcription initiation factor TIF-1A (显示 RRN3 抗体).
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
avian myelocytomatosis viral oncogene homolog
, class E basic helix-loop-helix protein 39
, myc proto-oncogene protein
, myc-related translation/localization regulatory factor
, proto-oncogene c-Myc
, transcription factor p64
, v-myc myelocytomatosis viral oncogene homolog
, c-myc proto-oncogene
, avian myelocytomatosis viral (v-myc) oncogene homolog
, Avian myelocytomatosis viral (v-myc) oncogene homolog
, myelocytomatosis viral oncogene homolog
, v-myc avian myelocytomatosis viral oncogene homolog
, cellular myelocytomatosis oncogene
, Proto-oncogene c-Myc
, Transcription factor p64
, transcriptional regulator Myc-A
, MYC II
, transcriptional regulator Myc-B
, Myc proto-oncogene protein
, CG10798 gene product from transcript CG10798-RB
, Diminutive protein
, lethal (1) G0354
, lethal (1) G0359