PARD6A 产品
(Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
Categories
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
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Featured PARD6A Categories
Recommended PARD6A 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (3)
Cat. No.
ABIN526360
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, FACS
Validations
- (3)
Cat. No.
ABIN185152
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
- (2)
Cat. No.
ABIN7162663
Quantity
100 μg
Datasheet
Datasheet
Recommended PARD6A 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7556365
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7550444
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1313999
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our PARD6A Products
: "Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier." in: Nature communications, Vol. 7, pp. 11876, (2016) (PubMed).: "Actin-interacting protein 1 controls assembly and permeability of intestinal epithelial apical junctions." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 308, Issue 9, pp. G745-56, (2015) (PubMed).
: "The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1." in: Journal of cell science, Vol. 113 ( Pt 18), pp. 3267-75, (2000) (PubMed).
Synonyms and alternative names related to PARD6A
par-6 partitioning defective 6 homolog alpha (C. elegans) (PARD6A), par-6 family cell polarity regulator alpha (PARD6A), par-6 family cell polarity regulator alpha (Pard6a), Partitioning defective protein 6 (par-6), 0710008C04Rik, 2610010A15Rik, Par-6, Par-6a, PAR-6A, Par6, PAR6, Par6a, PAR6alpha, Par6c, PAR6C, PARD6A, TAX40, Tip-40, TIP-40Protein level used designations for PARD6A
- par-6 partitioning defective 6 homolog alpha (C. elegans)
- partitioning defective 6 homolog alpha
- PAR-6 alpha
- PAR-6A
- Tax interaction protein 40
- partitioning defective protein 6A
- Tax-interacting protein 40
- par-6 partitioning defective 6 homolog alpha
- partitioning defective-6 homolog alpha
- partitioning-defective protein 6
- tax interaction protein 40
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