PAK6 抗体
(P21-Activated Kinase 6 (PAK6))
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013].
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79 results
PAK6
适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 山羊, 豚鼠
WB
宿主: 兔
Polyclonal
unconjugated
1 image
Latest Publications for our PAK6 抗体
: "Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein." in: Oncogene, Vol. 37, Issue 13, pp. 1730-1742, (2019) (PubMed).: "Chronic exposure to cigarette smoke leads to activation of p21 (RAC1)-activated kinase 6 (PAK6) in non-small cell lung cancer cells." in: Oncotarget, Vol. 7, Issue 38, pp. 61229-61245, (2016) (PubMed).
: "Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 7, pp. 3759-66, (2012) (PubMed).
: "Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase." in: The Journal of biological chemistry, Vol. 280, Issue 5, pp. 3323-30, (2005) (PubMed).
: "Mechanism of p21-activated kinase 6-mediated inhibition of androgen receptor signaling." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1922-31, (2004) (PubMed).
: "Identification of an autoinhibitory domain of p21-activated protein kinase 5." in: The Journal of biological chemistry, Vol. 278, Issue 36, pp. 33621-4, (2003) (PubMed).
: "p21-activated kinases: three more join the Pak." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 7, pp. 713-7, (2002) (PubMed).
: "AR and ER interaction with a p21-activated kinase (PAK6)." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 1, pp. 85-99, (2002) (PubMed).
: "Cloning and characterization of PAK5, a novel member of mammalian p21-activated kinase-II subfamily that is predominantly expressed in brain." in: Oncogene, Vol. 21, Issue 24, pp. 3939-48, (2002) (PubMed).
: "Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6." in: The Journal of biological chemistry, Vol. 276, Issue 18, pp. 15345-53, (2001) (PubMed).
Aliases for PAK6 抗体
p21 (RAC1) activated kinase 6 (PAK6) 抗体p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6) 抗体
p21 (RAC1) activated kinase 6 (Pak6) 抗体
p21 protein (Cdc42/Rac)-activated kinase 6b (pak6b) 抗体
p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6) 抗体
4732456M09 抗体
PAK5 抗体
pak6 抗体
si:ch211-158b22.3 抗体
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