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PAK3 产品

(PAK3)

Categories

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Featured PAK3 Categories

PAK3 抗体

High quality antibodies with extensive validation data.

PAK3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PAK3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (4)
Cat. No. ABIN518612
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB, ELISA, IHC, Neut, FACS, ICC
Validations
  • (4)
Cat. No. ABIN5611206
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (5)
Cat. No. ABIN3028914
Quantity 0.4 mL
Datasheet Datasheet

Recommended PAK3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380787
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended PAK3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
Cat. No. ABIN5570580
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5570579
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1313925
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PAK3 Products

Wang, Gratzke, Tamalunas, Wiemer, Ciotkowska, Rutz, Waidelich, Strittmatter, Liu, Stief, Hennenberg: "P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153312, (2016) (PubMed).

Valente, Turacchio, Mariggiò, Pagliuso, Gaibisso, Di Tullio, Santoro, Formiggini, Spanò, Piccini, Polishchuk, Colanzi, Luini, Corda: "A 14-3-3? dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIII? to regulate post-Golgi carrier formation." in: Nature cell biology, Vol. 14, Issue 4, pp. 343-54, (2012) (PubMed).

Kitano, Schwarz, Nickel, Pääbo: "Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees." in: Molecular biology and evolution, Vol. 20, Issue 8, pp. 1281-9, (2003) (PubMed).

Synonyms and alternative names related to PAK3

p21 (RAC1) activated kinase 3 (PAK3), p21 protein (Cdc42/Rac)-activated kinase 3 (Pak3), p21 (RAC1) activated kinase 3 (Pak3), p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog (pak3.L), beta-PAK, bPAK, bpak, CDKN1A, cdkn1a, hPAK3, MRX30, mrx30, MRX47, mrx47, OPHN3, ophn3, PAK-3, pak3, pak3-A, PAK3beta, pak3beta, Pak65alpha, Pak65beta, Stk4, XPak3

Protein level used designations for PAK3

  • PAK-3
  • beta-PAK
  • oligophrenin-3
  • p21 (CDKN1A)-activated kinase 3
  • p21-activated kinase 3
  • serine/threonine-protein kinase PAK 3
  • CDC42/RAC effector kinase PAK-B
  • p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related)
  • p65-PAK
  • PAK3a protein
  • PAK3d protein
  • serine/threonine protein kinase (p21-activated kinase 3)
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