PAK1/2/3 抗体
(P21-Activated Kinases 1/2/3 (PAK1/2/3))
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].
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Latest Publications for our PAK1/2/3 抗体
: "P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells." in: Molecular carcinogenesis, Vol. 56, Issue 5, pp. 1515-1525, (2017) (PubMed).: "Very-low and low-density lipoproteins induce neutral lipid accumulation and impair migration in monocyte subsets." in: Scientific reports, Vol. 6, pp. 20038, (2016) (PubMed).
: "Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells." in: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1680-95, (2005) (PubMed).
: "VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam." in: Molecular biology of the cell, Vol. 13, Issue 4, pp. 1175-89, (2002) (PubMed).
: "P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium." in: The EMBO journal, Vol. 21, Issue 20, pp. 5437-47, (2002) (PubMed).
: "Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala." in: Scientific reports, Vol. 7, Issue 1, pp. 13930 (PubMed).
Aliases for PAK1/2/3 抗体
p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog (pak1.S) 抗体p21 (RAC1) activated kinase 1 (PAK1) 抗体
pak 抗体
pak-1 抗体
pakalpha 抗体
X-PAK1 抗体
XPak1 抗体
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