OTU Domain, Ubiquitin Aldehyde Binding 1 抗体
(OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].
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Latest Publications for our OTU Domain, Ubiquitin Aldehyde Binding 1 抗体
: "OTUB1 inhibits CNS autoimmunity by preventing IFN-γ-induced hyperactivation of astrocytes." in: The EMBO journal, Vol. 38, Issue 10, (2019) (PubMed).: "Post-translational modification of the deubiquitinating enzyme otubain 1 modulates active RhoA levels and susceptibility to Yersinia invasion." in: The FEBS journal, Vol. 277, Issue 11, pp. 2515-30, (2010) (PubMed).
: "Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry." in: FEBS letters, Vol. 580, Issue 1, pp. 179-83, (2006) (PubMed).
Aliases for OTU Domain, Ubiquitin Aldehyde Binding 1 抗体
OTU deubiquitinase, ubiquitin aldehyde binding 1 (OTUB1) 抗体OTU domain, ubiquitin aldehyde binding 1 (Otub1) 抗体
OTU deubiquitinase, ubiquitin aldehyde binding 1 (Otub1) 抗体
OTU deubiquitinase, ubiquitin aldehyde binding 1b (otub1b) 抗体
OTU deubiquitinase, ubiquitin aldehyde binding 1 L homeolog (otub1.L) 抗体
OTU domain, ubiquitin aldehyde binding 1 (otub1) 抗体
OTU domain, ubiquitin aldehyde binding 1 (OTUB1) 抗体
similar to HSPC263 (RGD1565010) 抗体
OTU deubiquitinase, ubiquitin aldehyde binding 1a (otub1a) 抗体
AI850305 抗体
fa19h07 抗体
fb17f04 抗体
MGC131231 抗体
OTB1 抗体
OTU1 抗体
otub1 抗体
otub1l 抗体
wu:fa19h07 抗体
wu:fb17f04 抗体
zgc:92685 抗体
zgc:92839 抗体
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