This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Jaworski, Moreira, Li, Lee, Rodriguez: "A family of 12 human genes containing oxysterol-binding domains." in: Genomics, Vol. 78, Issue 3, pp. 185-96, (2001) (PubMed).