OPTN 蛋白
(Optineurin (OPTN))
This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
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14 results
custom-made
OPTN
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, ELISA, SDS
custom-made
OPTN
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, ELISA, SDS
OPTN
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
Greater than 90 % as determined by SDS-PAGE.
Aliases for OPTN 蛋白
optineurin (OPTN) 蛋白optineurin (optn) 蛋白
optineurin (Optn) 蛋白
optineurin L homeolog (optn.L) 蛋白
4930441O07Rik 蛋白
ALS12 蛋白
fip2 蛋白
FIP2 蛋白
Fip2 蛋白
fj52f04 蛋白
glc1e 蛋白
GLC1E 蛋白
hip7 蛋白
HIP7 蛋白
hypl 蛋白
HYPL 蛋白
nrp 蛋白
NRP 蛋白
si:ch211-240l19.3 蛋白
tfiiia-intp 蛋白
TFIIIA-INTP 蛋白
wu:fj52f04 蛋白
zgc:66386 蛋白
zgc:77868 蛋白
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