This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation. [provided by RefSeq, Jul 2008].
Dorrell, Erker, Schug, Kopp, Canaday, Fox, Smirnova, Duncan, Finegold, Sander, Kaestner, Grompe: "Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice." in: Genes & development, Vol. 25, Issue 11, pp. 1193-203, (2011) (PubMed).
Lu, Li, Kim, Bossuyt, Liu, Qiu, Wang, Halder, Finegold, Lee, Johnson: "Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 4, pp. 1437-42, (2010) (PubMed).
Dorrell, Erker, Lanxon-Cookson, Abraham, Victoroff, Ro, Canaday, Streeter, Grompe: "Surface markers for the murine oval cell response." in: Hepatology (Baltimore, Md.), Vol. 48, Issue 4, pp. 1282-91, (2008) (PubMed).
Aliases for ONECUT2 抗体
one cut domain, family member 2 (Onecut2) 抗体 one cut homeobox 2 (ONECUT2) 抗体 one cut homeobox 2 (Onecut2) 抗体 C730009D12 抗体 OC-2 抗体 Oc2 抗体 OC2 抗体 RGD1564677 抗体