Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity).
Jia, Cui, Meng, Xing, Shen, Wang, Liu, Wang, Lian, Zhang: "Malignant transformation of human gastric epithelium cells via reactive oxygen species production and Wnt/β-catenin pathway activation following 40-week exposure to ochratoxin A." in: Cancer letters, Vol. 372, Issue 1, pp. 36-47, (2016) (PubMed).