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NUP98 蛋白

(Nucleoporin 98kDa (NUP98))
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described. [provided by RefSeq, May 2010].

7 results :

NUP98 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
产品编号 ABIN1313248
 
NUP98 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
产品编号 ABIN1313246
 
NUP98 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant WB, SDS, ELISA
产品编号 ABIN7578586
 
NUP98 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % WB, SDS, Imm, PC
产品编号 ABIN7406317
 
NUP98 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % WB, SDS, Imm, PC
产品编号 ABIN7406383
 
NUP98 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, ELISA, IP
产品编号 ABIN3011009
 
NUP98 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % WB, SDS, ELISA, IP
产品编号 ABIN3011010
 
  • 类型 Protein
    • Protein
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Immunogen (Imm)
    • Immunoprecipitation (IP)
    • Positive Control (PC)
  • 适用
    • Human
    • Mouse
  • 图像
  • 抗体来源
    • Escherichia coli (E. coli)
    • Wheat germ
  • 抗原表位
    • AA 1-110
    • AA 1-606
    • AA 568-776
    • AA 629-894
  • 标记
    • His tag
    • GST tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Supplier
    • antibodies-online
    • Abbexa

Aliases for NUP98 蛋白

Nucleoporin 98-96kD (Nup98-96) 蛋白
nuclear pore complex protein Nup98-Nup96 (LOC408335) 蛋白
nucleoporin 98 (NUP98) 蛋白
nuclear pore complex protein Nup98-Nup96 (LOC587580) 蛋白
nucleoporin 98kDa (NUP98) 蛋白
nucleoporin 98 (Nup98) 蛋白
nucleoporin 98 (nup98) 蛋白
nucleoporin 98 L homeolog (nup98.L) 蛋白
4732457F17 蛋白
ADIR2 蛋白
AI849286 蛋白
CG10198 蛋白
CG10201 蛋白
Dmel\\CG10198 蛋白
GB12688 蛋白
im:7151238 蛋白
l(3)95BCd 蛋白
Nup-98 蛋白
Nup 96 蛋白
Nup96 蛋白
NUP96 蛋白
Nup 98 蛋白
Nup98 蛋白
NUP98 蛋白
nup98-96 蛋白
Nup98-Nup96 蛋白
Nup98/96 蛋白
nup145 蛋白
NUP196 蛋白
zgc:63593 蛋白
zgc:113968 蛋白
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