NSMCE1 蛋白
(Non-SMC Element 1 Homolog (NSMCE1))
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus.
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12 results
NSMCE1
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
Greater than 95 % as determined by SDS-PAGE
ELISA, WB
1 image
custom-made
NSMCE1
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
NSMCE1
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
NSMCE1
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aliases for NSMCE1 蛋白
NSE1 homolog, SMC5-SMC6 complex component (nsmce1) 蛋白NSE1 homolog, SMC5-SMC6 complex component (NSMCE1) 蛋白
NSE1 homolog, SMC5-SMC6 complex component L homeolog (nsmce1.L) 蛋白
NSE1 homolog, SMC5-SMC6 complex component (Nsmce1) 蛋白
2510027N19Rik 蛋白
NSE1 蛋白
NSMCE1 蛋白
RGD1307760 蛋白
zgc:92777 蛋白
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