NPRL2 抗体
(Nitrogen Permease Regulator-Like 2 (S. Cerevisiae) (NPRL2))
Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.
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Latest Publications for our NPRL2 抗体
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).: "The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells." in: Cancer research, Vol. 66, Issue 19, pp. 9682-90, (2006) (PubMed).
Aliases for NPRL2 抗体
nitrogen permease regulator-like 2 (Nprl2) 抗体NPR2 like, GATOR1 complex subunit S homeolog (nprl2.S) 抗体
NPR2 like, GATOR1 complex subunit (NPRL2) 抗体
NPR2-like, GATOR1 complex subunit (Nprl2) 抗体
NPR2 like, GATOR1 complex subunit (nprl2) 抗体
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