Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Nov 2010].
custom-made
NME2
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
custom-made
NME2
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, SDS, WB
Yokdang, Buxton, Buxton: "Measurement of human breast tumor cell-secreted shNDPK-B in a murine breast cancer model suggests its role in metastatic progression." in: Proceedings of the Western Pharmacology Society, Vol. 52, pp. 88-91, (2011) (PubMed).
Yokdang, Tellez, Tian, Norvell, Barsky, Valencik, Buxton: "A role for nucleotides in support of breast cancer angiogenesis: heterologous receptor signalling." in: British journal of cancer, Vol. 104, Issue 10, pp. 1628-40, (2011) (PubMed).