NK2 Homeobox 5 产品
(NK2 Homeobox 5 (NKX2-5))
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This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
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Featured NK2 Homeobox 5 Categories
NK2 Homeobox 5 抗体
High quality antibodies with extensive validation data.
NK2 Homeobox 5 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended NK2 Homeobox 5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (5)
Cat. No.
ABIN560515
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (6)
Cat. No.
ABIN570994
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), FACS
Validations
- (5)
Cat. No.
ABIN6243913
Quantity
200 μL
Datasheet
Datasheet
Recommended NK2 Homeobox 5 蛋白
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Reactivity
Source
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Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1777308
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3084656
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3134033
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our NK2 Homeobox 5 Products
: "iPSC-derived human cardiac progenitor cells improve ventricular remodelling via angiogenesis and interstitial networking of infarcted myocardium." in: Journal of cellular and molecular medicine, Vol. 20, Issue 2, pp. 323-32, (2016) (PubMed).: "Evaluation of sarcomeric organization in human pluripotent stem cell-derived cardiomyocytes." in: Methods in molecular biology (Clifton, N.J.), Vol. 1299, pp. 161-6, (2015) (PubMed).
: "Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5." in: PLoS ONE, Vol. 6, Issue 9, pp. e24812, (2011) (PubMed).
: "Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects." in: Circulation research, Vol. 103, Issue 6, pp. 580-90, (2008) (PubMed).
: "RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression." in: Nature genetics, Vol. 40, Issue 1, pp. 61-8, (2007) (PubMed).
: "GATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesis." in: Stem cells and development, Vol. 14, Issue 4, pp. 425-39, (2005) (PubMed).
: "Novel point mutation in the cardiac transcription factor CSX/NKX2.5 associated with congenital heart disease." in: Circulation journal : official journal of the Japanese Circulation Society, Vol. 66, Issue 6, pp. 561-3, (2002) (PubMed).
Synonyms and alternative names related to NK2 Homeobox 5
NK2 homeobox 5 (NKX2-5), NK2 homeobox 5 (Nkx2-5), NK2 homeobox 5 (nkx2.5), NK2 homeobox 5 S homeolog (nkx2-5.S), NK2 homeobox 5 (nkx2-5), AR2, CHNG5, CNKX-2.5, CSX, Csx, csx, CSX1, csx1, HLHS2, nk2.5, Nkx-2.5, nkx-2.5, NKX-2.5, nkx2-5, NKX2-5, Nkx2-5, nkx2-5b, NKX2.5, Nkx2.5, nkx2.5, NKX2E, nkx2e, NKX4-1, tinman, VSD3, XNkx-2.5, XNkx2-5, zgc:111912Protein level used designations for NK2 Homeobox 5
- NK2 transcription factor related, locus 5
- cardiac-specific homeobox 1
- homeobox protein CSX
- homeobox protein NK-2 homolog E
- homeobox protein Nkx-2.5
- tinman paralog
- Drosophila NK2 transcription factor related, locus 5
- cardiac-specific homeobox
- tinman homeobox homolog
- rNKx-2.5
- NK2 transcription factor related 5 b
- XNkx-2.5
- NK2 transcription factor related, locus 5 (Drosophila)
- transcription factor NKX2.5
- NK2 transcription factor locus 5-like
- Nkx2.5 protein
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