NFkB 抗体
(Nuclear Factor kappa B (NFkB))
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
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Rockland Original
Latest Publications for our NFkB 抗体
: "Indomethacin and juglone inhibit inflammatory molecules to induce apoptosis in colon cancer cells." in: Journal of biochemical and molecular toxicology, Vol. 34, Issue 2, pp. e22433, (2020) (PubMed).: "Scutellarin alleviates lipopolysaccharide-induced cognitive deficits in the rat: Insights into underlying mechanisms." in: International immunopharmacology, Vol. 54, pp. 311-319, (2018) (PubMed).
: "miR-221/222 promote cancer stem-like cell properties and tumor growth of breast cancer via targeting PTEN and sustained Akt/NF-κB/COX-2 activation." in: Chemico-biological interactions, Vol. 277, pp. 33-42, (2017) (PubMed).
: "Shuangtengbitong tincture treatment of collagen-induced arthritis via downregulation of the expression of IL-6, IL-8, TNF-? and NF-?B." in: Experimental and therapeutic medicine, Vol. 5, Issue 2, pp. 423-428, (2013) (PubMed).
: "Activation of NF-{kappa}B by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4." in: Cancer research, Vol. 71, Issue 4, pp. 1325-33, (2011) (PubMed).
: "Interactions of NF-kappaB with chromatin: the art of being at the right place at the right time." in: Nature immunology, Vol. 6, Issue 5, pp. 439-45, (2005) (PubMed).
: "Control of lymphocyte development by nuclear factor-kappaB." in: Nature reviews. Immunology, Vol. 5, Issue 6, pp. 435-45, (2005) (PubMed).
: "Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation." in: Trends in biochemical sciences, Vol. 30, Issue 1, pp. 43-52, (2005) (PubMed).
: "Role of acetaldehyde in the ethanol-induced impairment of hepatic glycoprotein secretion in the rat in vivo." in: Hepatology (Baltimore, Md.), Vol. 7, Issue 3, pp. 490-5, (1987) (PubMed).
Aliases for NFkB 抗体
nuclear factor kappa B subunit 1 (NFKB1) 抗体nuclear factor kappa B subunit 1 (Nfkb1) 抗体
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Nfkb1) 抗体
EBP-1 抗体
KBF1 抗体
NF-kappa-B 抗体
NF-kappaB 抗体
NF-kappaB1 抗体
NF-kB 抗体
NF-kB1 抗体
NF-KB1 抗体
NFkappaB 抗体
NFKB-p50 抗体
NFKB-p105 抗体
p50 抗体
p50/p105 抗体
p105 抗体
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