The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008].
Xu, Frankel, Jackson, Rotunda, Boshans, DSouza-Schorey, Foster: "Elevated phospholipase D activity in H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6." in: Molecular and cellular biology, Vol. 23, Issue 2, pp. 645-54, (2003) (PubMed).
Kinashi, Katagiri, Watanabe, Vanhaesebroeck, Downward, Takatsu: "Distinct mechanisms of alpha 5beta 1 integrin activation by Ha-Ras and R-Ras." in: The Journal of biological chemistry, Vol. 275, Issue 29, pp. 22590-6, (2000) (PubMed).
Goi, Rusanescu, Urano, Feig: "Ral-specific guanine nucleotide exchange factor activity opposes other Ras effectors in PC12 cells by inhibiting neurite outgrowth." in: Molecular and cellular biology, Vol. 19, Issue 3, pp. 1731-41, (1999) (PubMed).
Polakis, Weber, Nevins, Didsbury, Evans, Snyderman: "Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets." in: The Journal of biological chemistry, Vol. 264, Issue 28, pp. 16383-9, (1989) (PubMed).
Olofsson, Chardin, Touchot, Zahraoui, Tavitian: "Expression of the ras-related ralA, rho12 and rab genes in adult mouse tissues." in: Oncogene, Vol. 3, Issue 2, pp. 231-4, (1988) (PubMed).
Aliases for rala 抗体
v-ral simian leukemia viral oncogene A (ras related) (Rala) 抗体 RAS like proto-oncogene A (Rala) 抗体 RAS like proto-oncogene A (RALA) 抗体 3010001O15Rik 抗体 AW322615 抗体 Ral 抗体 RAL 抗体 Rasl1 抗体