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抗Mouse (Murine) TAF9 抗体:
抗Rat (Rattus) TAF9 抗体:
抗Human TAF9 抗体:
findings suggest that p53 (显示 TP53 抗体) sequesters TAF9 from GLI1 (显示 GLI1 抗体), which may contribute to inhibition of GLI1 (显示 GLI1 抗体) activity by p53 (显示 TP53 抗体)
TFIID TAF6 (显示 TAF6 抗体)-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 (显示 TAF6 抗体) and is modulated by TAF5 (显示 TAF5 抗体) protein.
TAF9 depletion severely disrupts TFIID, indicating that the observed ongoing transcription is initiated with at least partially TAF-free TATA-binding protein.
IL-1 (显示 IL1A 抗体)-inducible phosphorylation of p65 NFkB (显示 NFkBP65 抗体) is mediated by multiple protein kinases including IKKalpha (显示 CHUK 抗体), IKKbeta (显示 IKBKB 抗体), IKKepsilon (显示 IKBKE 抗体), TBK1 (显示 TBK1 抗体), and an unknown kinase and couples p65 (显示 GORASP1 抗体) to TAFII31 (显示 TAF9B 抗体)-mediated IL-8 (显示 IL8 抗体) transcription
histone fold domain mediated interaction enhances the DNA binding activity of each of the TAF6 (显示 TAF6 抗体)-TAF9 and TAF4b-TAF12 (显示 TAF12 抗体) pairs and of a histone-like octamer complex composed of the four TAFs
suggest a novel STAF65gamma-dependent function of STAGA-type complexes in cell proliferation and transcription activation by MYC postloading of TFIID and RNA polymerase II that involves direct recruitment of core Mediator
TAF9 functionally supports EKLF (显示 KLF1 抗体) activity by enhancing its ability to activate the beta-globin (显示 HBB 抗体) gene. TAF9 interacts with a conserved beta-globin (显示 HBB 抗体) downstream promoter element
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants encoding different isoforms.
, ATP-AMP transphosphorylase 6
, RNA polymerase II TBP-associated factor subunit G
, TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32 kDa
, adenylate kinase isoenzyme 6
, coilin-interacting nuclear ATPase protein
, dual activity adenylate kinase/ATPase
, transcription initiation factor TFIID 31 kDa subunit
, transcription initiation factor TFIID 32 kDa subunit
, transcription initiation factor TFIID subunit 9
, TAF9 RNA polymerase II, TATA box binding protein-associated factor
, adenylate kinase 6
, adrenal gland protein AD-004
, coilin interacting nuclear ATPase protein
, coilin interacting protein
, transcription initiation factor TFIID 31 kD subunit