neonatal Fc Receptor 抗体
(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].
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63 results
FcRn
适用: 人
BP, in vitro, in vivo
宿主: 兔
Chimeric
h22-0015
unconjugated
Recombinant Antibody
FcRn
适用: 人
BP, in vitro, in vivo
宿主: 小鼠
Monoclonal
h22-0015
unconjugated
Recombinant Antibody
Latest Publications for our neonatal Fc Receptor 抗体
: "Advanced human FcRn knock-in mice for pharmacokinetic profiling of therapeutic antibodies." in: Scientific reports, Vol. 15, Issue 1, pp. 27186, (2025) (PubMed).: "Zika Virus Infection and Antibody Neutralization in FcRn Expressing Placenta and Engineered Cell Lines." in: Vaccines, Vol. 10, Issue 12, (2022) (PubMed).
: "Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life." in: Communications biology, Vol. 5, Issue 1, pp. 832, (2022) (PubMed).
: "FcRn augments induction of tissue factor activity by IgG-containing immune complexes." in: Blood, Vol. 135, Issue 23, pp. 2085-2093, (2021) (PubMed).
: "FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity." in: The Journal of experimental medicine, Vol. 217, Issue 10, (2021) (PubMed).
: "An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics. ..." in: Science translational medicine, Vol. 12, Issue 565, (2021) (PubMed).
: "Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis." in: Science translational medicine, Vol. 12, Issue 566, (2021) (PubMed).
: "Placental transfer of 125 iodinated humanized immunoglobulin G2Δa in the cynomolgus monkey." in: Birth defects research, Vol. 112, Issue 1, pp. 105-117, (2020) (PubMed).
: "Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. ..." in: Science advances, Vol. 5, Issue 12, pp. eaax9586, (2020) (PubMed).
: "FcRn-Dependent Transcytosis of Monoclonal Antibody in Human Nasal Epithelial Cells In Vitro: A Prerequisite for a New Delivery Route for Therapy?" in: International journal of molecular sciences, Vol. 20, Issue 6, (2019) (PubMed).
Aliases for neonatal Fc Receptor 抗体
Fc fragment of IgG receptor and transporter (FCGRT) 抗体Fc fragment of IgG receptor and transporter (Fcgrt) 抗体
Fc receptor, IgG, alpha chain transporter (Fcgrt) 抗体
alpha-chain 抗体
FCRN 抗体
FcRn 抗体
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