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neonatal Fc Receptor 抗体

(neonatal Fc Receptor (FcRn))
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

63 results

FcRn 适用: 人 ELISA, IF, FACS, cELISA, Func 宿主: 小鼠 Monoclonal ADM31 unconjugated
Pubmed 16 references
产品编号 ABIN1774762
 
FcRn 适用: 人 ELISA, IF, FACS, cELISA 宿主: 小鼠 Monoclonal DVN24 unconjugated
Pubmed 6 references
产品编号 ABIN1774763
 
FcRn 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7156043
 
FcRn 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7441535
 
FcRn 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FCGRT-2932 unconjugated
产品编号 ABIN6939380
 
FcRn 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5F3D1 unconjugated
产品编号 ABIN7193245
 
FcRn 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2B3B11 unconjugated
产品编号 ABIN7193244
 
FcRn 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6140552
 
FcRn 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782616
 
FcRn 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN321108
 
FcRn 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN634564
 
FcRn 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044522
 
FcRn 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3044521
 
FcRn 适用: 人 WB 宿主: 兔 Polyclonal RB39368 unconjugated
产品编号 ABIN1537146
 
FcRn 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN7643299
 
FcRn 适用: Cynomolgus ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7176834
 
FcRn 适用: Cynomolgus ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7176832
 
FcRn 适用: Cynomolgus ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7176831
 
FcRn 适用: Cynomolgus 宿主: 兔 Polyclonal FITC
产品编号 ABIN7176833
 
FcRn 适用: 人 ELISA 宿主: 兔 Polyclonal HRP
产品编号 ABIN7156046
 
  • 类型 Primary
    • Primary
  • 应用范围
    • Western Blotting (WB)
    • ELISA
    • Immunohistochemistry (IHC)
    • Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    • Flow Cytometry (FACS)
    • Immunofluorescence (IF)
    • Immunoprecipitation (IP)
    • Immunocytochemistry (ICC)
    • Blocking Peptide (BP)
    • Cell-ELISA (cELISA)
    • In vitro Assay (in vitro)
    • In vivo Studies (in vivo)
    • Functional Studies (Func)
    • Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    • Immunostaining (ISt)
    • Staining Methods (StM)
    • Immunofluorescence (fixed cells) (IF/ICC)
  • 适用
    • Human
    • Mouse
    • Cynomolgus
    • Cow
    • Dog
    • Guinea Pig
    • Horse
    • Sheep
  • 论文引用
  • 图像
  • Preservative free only
  • Carrier free only
  • 抗体来源
    • Rabbit
    • Mouse
    • Human
    • Sheep
  • 克隆形成能力
    • Polyclonal
    • Monoclonal
    • Chimeric
  • 克隆
    • FCGRT-2932
    • h22-0015
    • 23H4
    • 2B3B11
    • 5F3D1
    • ADM31
    • DVN24
    • RB39368
  • 抗原表位
    • AA 330-357
    • AA 24-215
    • AA 24-297
    • C-Term
    • N-Term
    • AA 24-365
    • AA 22-301
    • AA 25-292
    • AA 25-300
    • AA 54-291
    • AA 56-291
    • Internal Region
  • 标记
    • 非结合性
    • Biotin
    • FITC
    • HRP
    • PE
    • APC
    • Alexa Fluor 488
    • Alexa Fluor 555
    • Alexa Fluor 594
    • Alexa Fluor 647
    • Alexa Fluor 680
    • Alexa Fluor 750
    • CF®405S
    • CF®488A
    • CF®568
    • CF®594
    • CF®640R
    • CF®647
    • CF®740
  • 抗体亚型
    • IgG
    • IgG2b
    • kappa
    • IgG1
    • IgG2b kappa
    • Ig Fraction
    • IgG kappa
    • IgG1 kappa
    • IgG2a
    • IgG2a kappa
    • IgG2b lambda
  • 蛋白类型
    • Recombinant Antibody
  • Format
    • Liquid
    • Lyophilized
  • Supplier
    • antibodies-online
    • Biotium
    • Signalway
    • USBio
    • Biomatik
    • Boster Bio
    • Abbexa
    • Abcepta
    • Angio-Proteomie
    • Aviva Systems Biology

Latest Publications for our neonatal Fc Receptor 抗体

Lee, Kyung, Park, Park, Lee, Kim, Lee, Jo, Jung, Lee: "Advanced human FcRn knock-in mice for pharmacokinetic profiling of therapeutic antibodies." in: Scientific reports, Vol. 15, Issue 1, pp. 27186, (2025) (PubMed).

Xu, He, Momben-Abolfath, Vertrees, Li, Norton, Struble: "Zika Virus Infection and Antibody Neutralization in FcRn Expressing Placenta and Engineered Cell Lines." in: Vaccines, Vol. 10, Issue 12, (2022) (PubMed).

Gjølberg, Frick, Mester, Foss, Grevys, Høydahl, Jørstad, Schlothauer, Sandlie, Moe, Andersen: "Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life." in: Communications biology, Vol. 5, Issue 1, pp. 832, (2022) (PubMed).

Cines, Zaitsev, Rauova, Rux, Stepanova, Krishnaswamy, Sarkar, Kowalska, Zhao, Mast, Blumberg, McCrae, Poncz, Hubbard, Pyzik, Blumberg: "FcRn augments induction of tissue factor activity by IgG-containing immune complexes." in: Blood, Vol. 135, Issue 23, pp. 2085-2093, (2021) (PubMed).

Hubbard, Pyzik, Rath, Kozicky, Sand, Gandhi, Grevys, Foss, Menzies, Glickman, Fiebiger, Roopenian, Sandlie, Andersen, Sly, Baker, Blumberg: "FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity." in: The Journal of experimental medicine, Vol. 217, Issue 10, (2021) (PubMed).

Bern, Nilsen, Ferrarese, Sand, Gjølberg, Lode, Davidson, Camire, Bækkevold, Foss, Grevys, Dalhus, Wilson, Høydahl, Christianson, Roopenian, Schlothauer, Michaelsen, Moe, Lombardi, Pinotti, Sandlie et al.: "An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics. ..." in: Science translational medicine, Vol. 12, Issue 565, (2021) (PubMed).

Casulleras, Flores-Costa, Duran-Güell, Alcaraz-Quiles, Sanz, Titos, López-Vicario, Fernández, Horrillo, Costa, de la Grange, Moreau, Arroyo, Clària: "Albumin internalizes and inhibits endosomal TLR signaling in leukocytes from patients with decompensated cirrhosis." in: Science translational medicine, Vol. 12, Issue 566, (2021) (PubMed).

Catlin, Mitchell, Potchoiba, OHara, Wang, Zhang, Weinbauer, Bowman: "Placental transfer of 125 iodinated humanized immunoglobulin G2Δa in the cynomolgus monkey." in: Birth defects research, Vol. 112, Issue 1, pp. 105-117, (2020) (PubMed).

Blumberg, Humphries, Jones, Pearce, Holgate, Hearn, Cheung, Mahmood, Del Tito, Graydon, Stolz, Bitonti, Purohit, de Graaf, Kacena, Andersen, Christianson, Roopenian, Hubbard, Gandhi, Lasseter, Pyzik et al.: "Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. ..." in: Science advances, Vol. 5, Issue 12, pp. eaax9586, (2020) (PubMed).

Bequignon, Dhommée, Angely, Thomas, Bottier, Escudier, Isabey, Coste, Louis, Papon, Gouilleux-Gruart: "FcRn-Dependent Transcytosis of Monoclonal Antibody in Human Nasal Epithelial Cells In Vitro: A Prerequisite for a New Delivery Route for Therapy?" in: International journal of molecular sciences, Vol. 20, Issue 6, (2019) (PubMed).

Aliases for neonatal Fc Receptor 抗体

Fc fragment of IgG receptor and transporter (FCGRT) 抗体
Fc fragment of IgG receptor and transporter (Fcgrt) 抗体
Fc receptor, IgG, alpha chain transporter (Fcgrt) 抗体
alpha-chain 抗体
FCRN 抗体
FcRn 抗体
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