N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 抗体
(N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Latest Publications for our N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 抗体
: "A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase." in: ACS chemical biology, Vol. 14, Issue 1, pp. 11-19, (2019) (PubMed).: "Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).
: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." in: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).
: "Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells." in: Biochimica et biophysica acta, Vol. 1841, Issue 4, pp. 552-62, (2014) (PubMed).
: "Ceramide biosynthesis and metabolism in trophoblast syncytialization." in: Molecular and cellular endocrinology, Vol. 362, Issue 1-2, pp. 48-59, (2012) (PubMed).
: "Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 228-43, (2012) (PubMed).
: "Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor." in: Molecular and cellular biology, Vol. 32, Issue 21, pp. 4419-31, (2012) (PubMed).
: "Genistein stimulates MCF-7 breast cancer cell growth by inducing acid ceramidase (ASAH1) gene expression." in: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19399-409, (2011) (PubMed).
: "Deregulation of sphingolipid metabolism in Alzheimer's disease." in: Neurobiology of aging, Vol. 31, Issue 3, pp. 398-408, (2010) (PubMed).
: "The cAMP-responsive element binding protein (CREB) regulates the expression of acid ceramidase (ASAH1) in H295R human adrenocortical cells." in: Biochimica et biophysica acta, Vol. 1791, Issue 8, pp. 706-13, (2009) (PubMed).
Aliases for N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 抗体
N-acylsphingosine amidohydrolase 1 (ASAH1) 抗体N-acylsphingosine amidohydrolase 1 (Asah1) 抗体
N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1) 抗体
N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog (asah1.L) 抗体
N-acylsphingosine amidohydrolase (acid ceramidase) 1a (asah1a) 抗体
Acid ceramidase (asah-1) 抗体
N-acylsphingosine amidohydrolase (acid ceramidase) 1b (asah1b) 抗体
2310081N20Rik 抗体
AC 抗体
ACDase 抗体
ASAH 抗体
Asah 抗体
asah1 抗体
ASAH1 抗体
MGC82286 抗体
PHP 抗体
PHP32 抗体
SMAPME 抗体
zgc:66026 抗体
zgc:101637 抗体
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