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NANS 蛋白

(N-Acetylneuraminic Acid Synthase (NANS))
This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively\; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008].

5 results

NANS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
产品编号 ABIN7124087
 
NANS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
产品编号 ABIN1311957
 
NANS 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pubmed 1 reference
产品编号 ABIN2726801
 
NANS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318801
 
NANS 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure SDS
产品编号 ABIN2130757
 
  • 类型 Protein
    • Protein
  • 应用范围
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • SDS-PAGE (SDS)
    • Standard (STD)
  • 适用
    • Human
  • 论文引用
  • 图像
  • Carrier free only
  • 抗体来源
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Wheat germ
  • 抗原表位
    • AA 1-359
  • 标记
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • 非结合性
  • 蛋白类型
    • Recombinant
  • Format
    • Liquid
    • Frozen
    • Lyophilized
  • Supplier
    • antibodies-online
    • OriGene

Latest Publications for our NANS 蛋白

van Karnebeek, Bonafé, Wen, Tarailo-Graovac, Balzano, Royer-Bertrand, Ashikov, Garavelli, Mammi, Turolla, Breen, Donnai, Cormier, Heron, Nishimura, Uchikawa, Campos-Xavier, Rossi, Hennet et al.: "NANS-mediated synthesis of sialic acid is required for brain and skeletal development. ..." in: Nature genetics, Vol. 48, Issue 7, pp. 777-84, (2016) (PubMed).

Aliases for NANS 蛋白

N-acetylneuraminate synthase L homeolog (nans.L) 蛋白
N-acetylneuraminate synthase (NANS) 蛋白
N-acetylneuraminate synthase (Nans) 蛋白
MGC84329 蛋白
SAS 蛋白
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