(Myosin, Heavy Polypeptide 10, Non-Muscle (MYH10))
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin\; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
Yuasa, Nakamura, Hijikata, Takeda: "Dystrophin deficiency in canine X-linked muscular dystrophy in Japan (CXMDJ) alters myosin heavy chain expression profiles in the diaphragm more markedly than in the tibialis cranialis muscle." in: BMC musculoskeletal disorders, Vol. 9, pp. 1, (2008) (PubMed).