The protein encoded by this gene binds to the N-terminus of the oncogenic protein C-MYC, enhancing the ability of C-MYC to activate E box-dependent transcription. The encoded protein is normally found in the cytoplasm, but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC. This protein may be involved in spermatogenesis. This gene can be silenced by microRNA-22. Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. [provided by RefSeq, Nov 2011].
Ramírez-Valle, Braunstein, Zavadil, Formenti, Schneider: "eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy." in: The Journal of cell biology, Vol. 181, Issue 2, pp. 293-307, (2008) (PubMed).
Cowell, Hawthorn: "The application of microarray technology to the analysis of the cancer genome." in: Current molecular medicine, Vol. 7, Issue 1, pp. 103-20, (2007) (PubMed).
Aliases for MYCBP 抗体
MYC binding protein (MYCBP) 抗体 MYC binding protein (Mycbp) 抗体 MYC binding protein (mycbp) 抗体 c-myc binding protein (TVAG_189750) 抗体 c-myc binding protein (PTRG_00444) 抗体 Myc binding protein (Mycbp) 抗体 c-myc binding protein (mycbp) 抗体 5730488M09Rik 抗体 AMY-1 抗体 Amy-1 抗体 amy-1 抗体 AMY1 抗体 AW552132 抗体 AW742590 抗体 zgc:136962 抗体