MXD3 产品
(MAX Dimerization Protein 3 (MXD3))
Categories
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008].
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Featured MXD3 Categories
Recommended MXD3 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (3)
Cat. No.
ABIN949698
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (2)
Cat. No.
ABIN7159074
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF, FACS
Validations
- (2)
Cat. No.
ABIN184841
Quantity
100 μg
Datasheet
Datasheet
Recommended MXD3 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1311688
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3083226
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3124290
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our MXD3 Products
: "Loss of MXD3 induces apoptosis of Reh human precursor B acute lymphoblastic leukemia cells." in: Blood cells, molecules & diseases, Vol. 54, Issue 4, pp. 329-35, (2015) (PubMed).: "MXD3 regulation of DAOY cell proliferation dictated by time course of activation." in: BMC cell biology, Vol. 15, pp. 30, (2014) (PubMed).
: "Targeted therapy with MXD3 siRNA, anti-CD22 antibody and nanoparticles for precursor B-cell acute lymphoblastic leukaemia." in: British journal of haematology, Vol. 167, Issue 4, pp. 487-99, (2014) (PubMed).
: "Histone deacetylase activity is necessary for left-right patterning during vertebrate development." in: BMC developmental biology, Vol. 11, pp. 29, (2011) (PubMed).
: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).
: "Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation." in: The EMBO journal, Vol. 14, Issue 22, pp. 5646-59, (1996) (PubMed).
Synonyms and alternative names related to MXD3
MAX dimerization protein 3 (mxd3), MAX dimerization protein 3 (MXD3), Max dimerization protein 3 (Mxd3), MAX dimerization protein 3 L homeolog (mxd3.L), 4631412E13Rik, BHLHC13, bHLHc13, Mad, Mad3, MAD3, MYX, Myx, zgc:66281Protein level used designations for MXD3
- MAX dimerization protein 3
- Max-associated protein 3
- Max-interacting transcriptional repressor MAD3
- class C basic helix-loop-helix protein 13
- max dimerization protein 3
- max dimerizer 3
- max-associated protein 3
- Mad3
- max-interacting transcriptional repressor MAD3
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