MVB12B 蛋白
(Multivesicular Body Subunit 12B (MVB12B))
The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
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6 results
custom-made
MVB12B
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
MVB12B
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
MVB12B
宿主: 人
宿主: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aliases for MVB12B 蛋白
multivesicular body subunit 12B (MVB12B) 蛋白multivesicular body subunit 12B (Mvb12b) 蛋白
multivesicular body subunit 12B S homeolog (mvb12b.S) 蛋白
multivesicular body subunit 12Ba (mvb12ba) 蛋白
2610200O14Rik 蛋白
2610528K11Rik 蛋白
AI414895 蛋白
C9orf28 蛋白
FAM125B 蛋白
Fam125b 蛋白
fam125b 蛋白
fam125ba 蛋白
mvb12b 蛋白
RGD1309709 蛋白
zgc:152929 蛋白
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