MUTYH 抗体
(MutY Homolog (E. Coli) (MUTYH))
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Latest Publications for our MUTYH 抗体
: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." in: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).: "Uncoupling genotoxic stress responses from circadian control increases susceptibility to mammary carcinogenesis." in: Oncotarget, Vol. 8, Issue 20, pp. 32752-32768, (2017) (PubMed).
: "Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia Coli Strain." in: Human mutation, Vol. 36, Issue 7, pp. 704-11, (2015) (PubMed).
: "Impaired 8-hydroxyguanine repair activity of MUTYH variant p.Arg109Trp found in a Japanese patient with early-onset colorectal cancer." in: Oxidative medicine and cellular longevity, Vol. 2014, pp. 617351, (2014) (PubMed).
: "Visualization of the physical and functional interaction between hMYH and hRad9 by Dronpa bimolecular fluorescence complementation." in: BMC molecular biology, Vol. 15, pp. 17, (2014) (PubMed).
: "Understanding the role of the Q338H MUTYH variant in oxidative damage repair." in: Nucleic acids research, Vol. 41, Issue 7, pp. 4093-103, (2013) (PubMed).
: "Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells." in: Carcinogenesis, Vol. 33, Issue 11, pp. 2301-9, (2012) (PubMed).
: "Human MutY homolog induces apoptosis in etoposide-treated HEK293 cells." in: Oncology letters, Vol. 4, Issue 6, pp. 1203-1208, (2012) (PubMed).
: "p73 protein regulates DNA damage repair." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 12, pp. 4406-14, (2011) (PubMed).
: "Effects of base excision repair proteins on mutagenesis by 8-oxo-7,8-dihydroguanine (8-hydroxyguanine) paired with cytosine and adenine." in: DNA repair, Vol. 9, Issue 5, pp. 542-50, (2010) (PubMed).
Aliases for MUTYH 抗体
mutY DNA glycosylase (MUTYH) 抗体mutY homolog (E. coli) (MUTYH) 抗体
mutY DNA glycosylase (mutyh) 抗体
A/G-specific adenine DNA glycosylase-like (LOC100373318) 抗体
mutY DNA glycosylase (Mutyh) 抗体
5730495A01Rik 抗体
CYP2C 抗体
MGC145569 抗体
MUTYH 抗体
Mutyha 抗体
Mutyhalpha 抗体
Mutyhb 抗体
Mutyhbeta 抗体
Mutyhc 抗体
MYH 抗体
Myh 抗体
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