This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
custom-made
MTMR3
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
MTMR3
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
myotubularin-related protein 3 (mtmr3) 蛋白 myotubularin related protein 3 (MTMR3) 蛋白 myotubularin related protein 3 L homeolog (mtmr3.L) 蛋白 myotubularin related protein 3 (mtmr3) 蛋白 myotubularin related protein 3 (Mtmr3) 蛋白 1700092A20Rik 蛋白 AI255150 蛋白 AW557713 蛋白 DKFZp459K2113 蛋白 FYVE-DSP1 蛋白 MGC68981 蛋白 MGC143436 蛋白 mKIAA0371 蛋白 ZFYVE10 蛋白