This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.[provided by RefSeq, Apr 2010].
custom-made
MTMR14
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
MTMR14
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Papp, Kovács, Billes, Varga, Tarnóci, Hackler, Puskás, Liliom, Tárnok, Schlett, Borsy, Pádár, Kovács, Hegedűs, Juhász, Komlós, Erdős, Gulyás, Vellai: "AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects." in: Autophagy, Vol. 12, Issue 2, pp. 273-86, (2016) (PubMed).
Aliases for MTMR14 蛋白
myotubularin related protein 14 (mtmr14) 蛋白 myotubularin-related protein 14 (LOC703936) 蛋白 myotubularin related protein 14 S homeolog (mtmr14.S) 蛋白 myotubularin related protein 14 (MTMR14) 蛋白 myotubularin related protein 14 (Mtmr14) 蛋白 1110061O04Rik 蛋白 AW553738 蛋白 C3orf29 蛋白 C76151 蛋白 fc14d11 蛋白 jumpy 蛋白 MGC131146 蛋白 RGD1304842 蛋白 wu:fc14d11 蛋白