This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012].
Xu, Shi, Gao, Mao, Zhao, Agrawal, Chisolm, Sui, Cui: "The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein." in: The Journal of biological chemistry, Vol. 277, Issue 50, pp. 48913-22, (2002) (PubMed).