This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012].
Oda, Arakawa, Tanaka, Matsuda, Tanikawa, Mori, Nishimori, Tamai, Tokino, Nakamura, Taya: "p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53." in: Cell, Vol. 102, Issue 6, pp. 849-62, (2000) (PubMed).
Boyd, Vlatkovic, Haines: "A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2." in: The Journal of biological chemistry, Vol. 275, Issue 41, pp. 31883-90, (2000) (PubMed).
Aliases for MTBP 抗体
MDM2 binding protein (MTBP) 抗体 Mdm2, transformed 3T3 cell double minute p53 binding protein (Mtbp) 抗体 AI429604 抗体 MDM2BP 抗体