Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). [provided by RefSeq, Jul 2008].
Tang, Zheng, Chen, Murphy, Kudlicka, Zhou, Farquhar: "hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis." in: The Journal of biological chemistry, Vol. 284, Issue 8, pp. 5414-24, (2009) (PubMed).
Aliases for MRPS27 抗体
mitochondrial ribosomal protein S27 (Mrps27) 抗体 mitochondrial ribosomal protein S27 (MRPS27) 抗体 mitochondrial ribosomal protein S27 L homeolog (mrps27.L) 抗体 2610028H14Rik 抗体 DKFZp459M1724 抗体 MRP-S27 抗体 S27mt 抗体