(Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 3 (TAX1BP3))
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
Oliver, He, Borthwick, Donne, Hampson, Hampson: "The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42." in: British journal of cancer, Vol. 104, Issue 2, pp. 324-31, (2011) (PubMed).
Aliases for TAX1BP3 抗体
Tax1 binding protein 3 (TAX1BP3) 抗体 Tax1 binding protein 3 (Tax1bp3) 抗体 Tax1 (human T cell leukemia virus type I) binding protein 3 (Tax1bp3) 抗体 Tax1 (human T-cell leukemia virus type I) binding protein 3 S homeolog (tax1bp3.S) 抗体 Tax1 (human T-cell leukemia virus type I) binding protein 3 (tax1bp3) 抗体 1300011C24Rik 抗体 RP23-263M10.10 抗体 tax1bp3 抗体 TIP-1 抗体 wu:fb37e03 抗体 wu:fc23g08 抗体 zgc:55513 抗体