MMP12 抗体
(Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008].
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Latest Publications for our MMP12 抗体
: "Embryonal Origin of Metanephric Adenoma and its Differential Diagnosis." in: Anticancer research, Vol. 38, Issue 12, pp. 6663-6667, (2019) (PubMed).: "Dietary DNA Attenuates the Degradation of Elastin Fibers in the Aortic Wall in Nicotine-Administrated Mice." in: Journal of nutritional science and vitaminology, Vol. 64, Issue 4, pp. 271-276, (2019) (PubMed).
: "Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice." in: Food & function, Vol. 8, Issue 8, pp. 2829-2835, (2017) (PubMed).
: "Down-regulation of Toll-like Receptor TLR4 Is Associated with HPV DNA Integration in Penile Carcinoma." in: Anticancer research, Vol. 37, Issue 10, pp. 5515-5519, (2017) (PubMed).
: "Nkx2-5 Is Expressed in Atherosclerotic Plaques and Attenuates Development of Atherosclerosis in Apolipoprotein E-Deficient Mice." in: Journal of the American Heart Association, Vol. 5, Issue 12, (2017) (PubMed).
: "Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity. ..." in: The Journal of allergy and clinical immunology, Vol. 129, Issue 3, pp. 655-663.e8, (2012) (PubMed).
: "Optimization of total protein and activity assays for the detection of MMP-12 in induced human sputum." in: BMC pulmonary medicine, Vol. 10, pp. 40, (2010) (PubMed).
: "Blockade of the c-Jun amino terminal kinase prevents crescent formation and halts established anti-GBM glomerulonephritis in the rat." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 89, Issue 4, pp. 470-84, (2009) (PubMed).
: "Association of MMP1, MMP3, MMP9, and MMP12 polymorphisms with risk and clinical course of multiple sclerosis in a Polish population." in: Journal of neuroimmunology, Vol. 214, Issue 1-2, pp. 113-7, (2009) (PubMed).
: "Compression of the right atrium due to coexistence of diaphragmatic eventration and Chilaiditi's syndrome." in: The Thoracic and cardiovascular surgeon, Vol. 56, Issue 6, pp. 365-7, (2008) (PubMed).
Aliases for MMP12 抗体
matrix metallopeptidase 12 (MMP12) 抗体matrix metallopeptidase 12 (Mmp12) 抗体
AV378681 抗体
HME 抗体
ME 抗体
Mme 抗体
MME 抗体
Mmel 抗体
MMP-12 抗体
MMP12 抗体
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