MICA 蛋白
(MHC Class I Polypeptide-Related Sequence A (MICA))
MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010].
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23 results
MALS verified
MICA
宿主: 人
宿主: HEK-293 Cells
Recombinant
90 %
Latest Publications for our MICA 蛋白
: "Shedding of CD16 disassembles the NK cell immune synapse and boosts serial engagement of target cells." in: The Journal of cell biology, Vol. 217, Issue 9, pp. 3267-3283, (2018) (PubMed).: "Targeted activation of human V?9V?2-T cells controls epstein-barr virus-induced B cell lymphoproliferative disease." in: Cancer cell, Vol. 26, Issue 4, pp. 565-76, (2014) (PubMed).
Aliases for MICA 蛋白
MHC class I polypeptide-related sequence A (MICA) 蛋白MIC-A 蛋白
PERB11.1 蛋白
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