MIB2 抗体
(E3 ubiquitin-protein ligase MIB2 (MIB2))
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors (By similarity).
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Latest Publications for our MIB2 抗体
: "MIB2 variants altering NOTCH signalling result in left ventricle hypertrabeculation/non-compaction and are associated with Ménétrier-like gastropathy. ..." in: Human molecular genetics, Vol. 26, Issue 1, pp. 33-43, (2016) (PubMed).: "The E3 ubiquitin ligase mind bomb-2 (MIB2) protein controls B-cell CLL/lymphoma 10 (BCL10)-dependent NF-κB activation." in: The Journal of biological chemistry, Vol. 286, Issue 43, pp. 37147-57, (2011) (PubMed).
: "Mind bomb-2 is an E3 ligase that ubiquitinates the N-methyl-D-aspartate receptor NR2B subunit in a phosphorylation-dependent manner." in: The Journal of biological chemistry, Vol. 283, Issue 1, pp. 301-10, (2007) (PubMed).
Aliases for MIB2 抗体
mindbomb E3 ubiquitin protein ligase 2 (MIB2) 抗体mindbomb E3 ubiquitin protein ligase 2 (Mib2) 抗体
mindbomb E3 ubiquitin protein ligase 2 (mib2) 抗体
mindbomb E3 ubiquitin protein ligase 2 S homeolog (mib2.S) 抗体
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