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MED28 产品

(Mediator Complex Subunit 28 (MED28))
May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

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Featured MED28 Categories

MED28 抗体

High quality antibodies with extensive validation data.

MED28 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MED28 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MED28 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7159148
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7244117
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN500268
Quantity 0.1 mg
Datasheet Datasheet

Recommended MED28 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1745725
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1744506
Quantity 96 tests
Datasheet Datasheet
Reactivity Monkey
Analytical Method
Validations
Cat. No. ABIN1770520
Quantity 96 tests
Datasheet Datasheet

Recommended MED28 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123873
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3083583
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3127617
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our MED28 Products

Brass, Dykxhoorn, Benita, Yan, Engelman, Xavier, Lieberman, Elledge: "Identification of host proteins required for HIV infection through a functional genomic screen." in: Science (New York, N.Y.), Vol. 319, Issue 5865, pp. 921-6, (2008) (PubMed).

Beyer, Beauchamp, Lee, Gusella, Näär, Ramesh: "Mediator subunit MED28 (Magicin) is a repressor of smooth muscle cell differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 44, pp. 32152-7, (2007) (PubMed).

Sato, Tomomori-Sato, Parmely, Florens, Zybailov, Swanson, Banks, Jin, Cai, Washburn, Conaway, Conaway: "A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology." in: Molecular cell, Vol. 14, Issue 5, pp. 685-91, (2004) (PubMed).

Synonyms and alternative names related to MED28

mediator complex subunit 28 (MED28), mediator complex subunit 28 (Med28), mediator complex subunit 28 (med28), 1500003D12Rik, AI451633, AU045690, EG1, Eg1, FKSG20, magicin, RGD1305875, wu:fc74b11, zgc:103633

Protein level used designations for MED28

  • mediator of RNA polymerase II transcription, subunit 28 homolog
  • mediator complex subunit 28
  • endothelial-derived gene 1
  • endothelial-derived protein 1
  • mediator of RNA polymerase II transcription subunit 28
  • merlin and Grb2-interacting cytoskeletal protein
  • tumor angiogenesis marker EG-1
  • endothelial-derived
  • mediator of RNA polymerase II transcription, subunit 28
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