MED23 抗体
(Mediator Complex Subunit 23 (MED23))
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012].
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Latest Publications for our MED23 抗体
: "Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development." in: Nature communications, Vol. 7, pp. 11149, (2016) (PubMed).: "LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation." in: Neuron, Vol. 86, Issue 3, pp. 696-710, (2015) (PubMed).
: "The Mediator subunit MED23 couples H2B mono-ubiquitination to transcriptional control and cell fate determination." in: The EMBO journal, Vol. 34, Issue 23, pp. 2885-902, (2015) (PubMed).
: "T-cells null for the MED23 subunit of mediator express decreased levels of KLF2 and inefficiently populate the peripheral lymphoid organs." in: PLoS ONE, Vol. 9, Issue 7, pp. e102076, (2015) (PubMed).
: "The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation." in: Experimental neurology, Vol. 253, pp. 126-37, (2014) (PubMed).
: "Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity." in: Cell research, Vol. 24, Issue 10, pp. 1250-65, (2014) (PubMed).
: "Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation." in: Journal of virology, Vol. 86, Issue 15, pp. 8198-209, (2012) (PubMed).
: "Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves." in: Molecular and cellular biology, Vol. 32, Issue 1, pp. 199-205, (2011) (PubMed).
: "Core promoter recognition complex changes accompany liver development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 10, pp. 3906-11, (2011) (PubMed).
: "Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3." in: The EMBO journal, Vol. 27, Issue 10, pp. 1447-57, (2008) (PubMed).
Aliases for MED23 抗体
Mediator complex subunit 23 (MED23) 抗体mediator complex subunit 23 (MED23) 抗体
mediator complex subunit 23 (med23) 抗体
mediator of RNA polymerase II transcription subunit 23 (LOC412332) 抗体
mediator complex subunit 23 (Med23) 抗体
mediator complex subunit 23 L homeolog (med23.L) 抗体
Mediator of RNA polymerase II transcription subunit 23 (sur-2) 抗体
130kDa 抗体
3000002A17Rik 抗体
ARC130 抗体
CG3695 抗体
CRSP3 抗体
Crsp3 抗体
crsp3 抗体
CRSP130 抗体
CRSP133 抗体
Dmel\\CG3695 抗体
DRIP130 抗体
dSUR2 抗体
dTRAP150beta 抗体
ESTM7 抗体
Gal11/SUR2 抗体
Med23 抗体
MED23 抗体
mKIAA1216 抗体
MRT18 抗体
si:ch211-272f15.2 抗体
SUR-2 抗体
SUR2 抗体
Sur2 抗体
Trap150 抗体
Trap150beta 抗体
X83317 抗体
zgc:91979 抗体
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