MBD5 蛋白
(Methyl-CpG Binding Domain Protein 5 (MBD5))
This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause mental retardation autosomal dominant type 1. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined. [provided by RefSeq, Mar 2010].
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6 results
custom-made
MBD5
宿主: 小鼠
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
MBD5
宿主: 人
宿主: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
Aliases for MBD5 蛋白
methyl-CpG binding domain protein 5 (MBD5) 蛋白methyl-CpG binding domain protein 5 (mbd5) 蛋白
methyl-CpG binding domain protein 5 (Mbd5) 蛋白
9430004D19Rik 蛋白
AA536666 蛋白
AI426407 蛋白
C030040A15Rik 蛋白
MBD5 蛋白
MRD1 蛋白
OTTMUSG00000012483 蛋白
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