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RAF1 蛋白

(V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))
This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008].
RAF1 Protein (AA 1-648) (GST tag) RAF1 Protein (AA 1-648) (GST tag) RAF1 Protein (AA 1-648) (GST tag) (ABIN1317314)

RAF1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

RAF1 Protein (AA 306-648, Tyr340Asp-Mutant, Tyr341Asp-Mutant) RAF1 Protein (AA 306-648, Tyr340Asp-Mutant, Tyr341Asp-Mutant) RAF1 Protein (AA 306-648, Tyr340Asp-Mutant, Tyr341Asp-Mutant) (ABIN5569962)

RAF1 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active

RAF1 Protein (AA 1-130) (GST tag) RAF1 Protein (AA 1-130) (GST tag) RAF1 Protein (AA 1-130) (GST tag) (ABIN1317315)

RAF1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

RAF1 蛋白 by Grade

Find RAF1 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

RAF1 蛋白 by Origin

Find RAF1 蛋白 for a variety of species such as anti-Human RAF1, anti-Mouse RAF1, anti-Rat RAF1. The species listed below are among those available. Click on a link to go to the corresponding products.

RAF1 蛋白 by Source

Here you will find RAF1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

RAF1 蛋白 by 蛋白类型

Here you can find RAF1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

RAF1 蛋白 by 应用范围

Find RAF1 蛋白 validated for a specific application such as ELISA, SDS, WB, Func. Some of the available applications are listed below. Click on a link to go to the corresponding products.

RAF1 蛋白 by 生物活性

Find RAF1 蛋白 with a specific 生物活性. The 生物活性 listed below are among those available. Click on a link to go to the corresponding products.

Popular RAF1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1317314
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5569962
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1317315
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094878
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136985
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505245
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
Cat. No. ABIN5509125
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus
Validations
Cat. No. ABIN7507820
Quantity 5 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5710215
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2730424
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1473943
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our RAF1 蛋白

Rodríguez-Muñoz, de la Torre-Madrid, Sánchez-Blázquez, Garzón: "NO-released zinc supports the simultaneous binding of Raf-1 and PKC? cysteine-rich domains to HINT1 protein at the mu-opioid receptor." in: Antioxidants & redox signaling, Vol. 14, Issue 12, pp. 2413-25, (2011) (PubMed).

Aliases for RAF1 蛋白

Raf-1 proto-oncogene, serine/threonine kinase (RAF1) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase (Raf1) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase a (raf1a) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase (raf1) 蛋白
v-raf-leukemia viral oncogene 1 (Raf1) 蛋白
Raf-1 proto-oncogene, serine/threonine kinase S homeolog (raf1.S) 蛋白
6430402F14Rik 蛋白
AA990557 蛋白
BB129353 蛋白
c-Raf 蛋白
c-raf 蛋白
CRAF 蛋白
craf 蛋白
cRaf 蛋白
Craf1 蛋白
D830050J10Rik 蛋白
NS5 蛋白
raf 蛋白
Raf-1 蛋白
raf1 蛋白
RAF1 蛋白
v-Raf 蛋白
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