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MAVS 产品

(Mitochondrial Antiviral Signaling Protein (MAVS))

Categories

This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

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Featured MAVS Categories

MAVS 抗体

High quality antibodies with extensive validation data.

MAVS ELISA试剂盒

Reliable ELISA kits for a wide range of species.

MAVS 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended MAVS 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (7)
Cat. No. ABIN6143583
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (5)
Cat. No. ABIN5518935
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6265988
Quantity 100 μL
Datasheet Datasheet

Recommended MAVS ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957844
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1142669
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1142670
Quantity 96 tests
Datasheet Datasheet

Recommended MAVS 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123974
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123973
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123975
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our MAVS Products

Qian, Fan, Liu, Wu, Zhang, Cui, Zhou, Hu, Wei, Chen, Li, Qian: "Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage." in: Journal of virology, Vol. 91, Issue 16, (2017) (PubMed).

He, Zhu, Wen, Yuan, Hu, Chen, An, Dong, Lin, Yu, Wu, Yang, Cai, Li, Li: "Dengue Virus Subverts Host Innate Immunity by Targeting Adaptor Protein MAVS." in: Journal of virology, Vol. 90, Issue 16, pp. 7219-30, (2016) (PubMed).

Morikawa, Gouttenoire, Hernandez, Dao Thi, Tran, Lange, Dill, Heim, Donzé, Penin, Quadroni, Moradpour: "Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease." in: Hepatology (Baltimore, Md.), Vol. 59, Issue 2, pp. 423-33, (2014) (PubMed).

Klarquist, Hennies, Lehn, Reboulet, Feau, Janssen: "STING-mediated DNA sensing promotes antitumor and autoimmune responses to dying cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 12, pp. 6124-34, (2014) (PubMed).

Wang, Xi, Lei, Zhang, Cui, Wang, Jin, Zhao: "Enterovirus 71 protease 2Apro targets MAVS to inhibit anti-viral type I interferon responses." in: PLoS pathogens, Vol. 9, Issue 3, pp. e1003231, (2013) (PubMed).

Ichinohe, Pang, Iwasaki: "Influenza virus activates inflammasomes via its intracellular M2 ion channel." in: Nature immunology, Vol. 11, Issue 5, pp. 404-10, (2010) (PubMed).

Bellecave, Sarasin-Filipowicz, Donzé, Kennel, Gouttenoire, Meylan, Terracciano, Tschopp, Sarrazin, Berg, Moradpour, Heim: "Cleavage of mitochondrial antiviral signaling protein in the liver of patients with chronic hepatitis C correlates with a reduced activation of the endogenous interferon system." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 4, pp. 1127-36, (2010) (PubMed).

Michallet, Meylan, Ermolaeva, Vazquez, Rebsamen, Curran, Poeck, Bscheider, Hartmann, König, Kalinke, Pasparakis, Tschopp: "TRADD protein is an essential component of the RIG-like helicase antiviral pathway." in: Immunity, Vol. 28, Issue 5, pp. 651-61, (2008) (PubMed).

Seth, Sun, Chen: "Antiviral innate immunity pathways." in: Cell research, Vol. 16, Issue 2, pp. 141-7, (2006) (PubMed).

Xu, Wang, Han, Li, Zhai, Shu: "VISA is an adapter protein required for virus-triggered IFN-beta signaling." in: Molecular cell, Vol. 19, Issue 6, pp. 727-40, (2005) (PubMed).

Synonyms and alternative names related to MAVS

mitochondrial antiviral signaling protein (MAVS), mitochondrial antiviral signaling protein (Mavs), mitochondrial antiviral signaling protein (mavs), CARDIF, cardif, D430028G21Rik, IPS-1, IPS1, VISA, Visa, wu:fj20d04, zgc:158392

Protein level used designations for MAVS

  • CARD adapter inducing interferon beta
  • CARD adaptor inducing IFN-beta
  • IFN-B promoter stimulator 1
  • interferon beta promoter stimulator protein 1
  • mitochondrial antiviral-signaling protein
  • putative NF-kappa-B-activating protein 031N
  • virus-induced signaling adaptor
  • virus-induced-signaling adapter
  • virus-induced signaling adapter
  • IFN-beta promoter stimulator-1
  • mitochondrial anti-viral signaling protein
  • mitochondrial IFN-beta promoter stimulator 1
  • IPS-1
  • interferon-beta promoter stimulator protein 1
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